We are live on ! Find out more
SNDX icon

Syndax Pharmaceuticals

216 hedge funds and large institutions have $953M invested in Syndax Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 31 funds opening new positions, 86 increasing their positions, 66 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

30% more repeat investments, than reductions

Existing positions increased: 86 | Existing positions reduced: 66

15% more call options, than puts

Call options by funds: $14.4M | Put options by funds: $12.5M

0.86% more ownership

Funds ownership: 117.37%118.22% (+0.86%)

1% less funds holding

Funds holding: 218216 (-2)

3% less first-time investments, than exits

New positions opened: 31 | Existing positions closed: 32

24% less capital invested

Capital invested by funds: $1.25B → $953M (-$302M)

30% less funds holding in top 10

Funds holding in top 10: 107 (-3)

Holders
216
Holders Change
-2
Holders Change %
-0.92%
% of All Funds
2.84%
Holding in Top 10
7
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-30%
% of All Funds
0.09%
New
31
Increased
86
Reduced
66
Closed
32
Calls
$14.4M
Puts
$12.5M
Net Calls
+$1.84M
Net Calls Change
-$8.34M
Name Holding Trade Value Shares
Change
Change in
Stake
CWM
201
Crowley Wealth Management
Delaware
$1.87K
IA
202
IFP Advisors
Florida
$1.56K
BBHC
203
Brown Brothers Harriman & Co
New York
$1.2K +$1.41K +128 New
PA
204
Parallel Advisors
California
$899 -$2.6K -236 -71%
S
205
SignatureFD
Georgia
$684 -$14.5K -1,321 -95%
MPWT
206
MassMutual Private Wealth & Trust
Connecticut
$665 +$275 +25 +54%
RIL
207
Rothschild Investment LLC
Illinois
$515 -$825 -75 -58%
TPCW
208
TD Private Client Wealth
New York
$506 +$594 +54 New
SAM
209
Smartleaf Asset Management
Massachusetts
$461 -$6.39K -581 -92%
GI
210
GAMMA Investing
California
$403 -$396 -36 -46%
TWD
211
True Wealth Design
Ohio
$235 -$792 -72 -74%
FFA
212
Farther Finance Advisors
California
$215 -$528 -48 -68%
EWA
213
EverSource Wealth Advisors
Alabama
$131 -$2.58K -234 -94%
Comerica Bank
214
Comerica Bank
Texas
$112 -$11.6K -1,050 -99%
PHS
215
PFM Health Sciences
California
-$11.4M -926,424 Closed
OCA
216
Octagon Capital Advisors
New York
-$11.1M -904,000 Closed
TI
217
Trexquant Investment
Connecticut
-$4.75M -386,263 Closed
ECM
218
ExodusPoint Capital Management
New York
-$3.86M -314,407 Closed
PE
219
Point72 Europe
United Kingdom
-$2.27M -184,683 Closed
PBM
220
Propel Bio Management
California
-$2.25M -183,259 Closed
TIM
221
Thornburg Investment Management
New Mexico
-$16.1M -130,746 Closed
AI
222
Axiom Investors
Connecticut
-$641K -52,204 Closed
CF
223
Corebridge Financial
Texas
-$495K -40,255 Closed
AIM
224
Aigen Investment Management
New York
-$297K -24,158 Closed
Cerity Partners
225
Cerity Partners
New York
-$295K -24,048 Closed

SNDX Hedge Fund Activity: Q2 2025 in Review

216 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Syndax Pharmaceuticals (SNDX) for Q2 2025, worth a combined $953M — down 24% from $1.25B a quarter earlier.

Sellers outnumbered buyers: 32 funds closed out of SNDX and 31 opened new positions — a net loss of 1 holder — while 66 trimmed existing stakes and 86 added.

The largest buyer was BlackRock, adding an estimated $21.1M. The largest seller was Citadel Advisors, cutting an estimated $25M.

  • 216 institutional investors held Syndax Pharmaceuticals (SNDX) as of Q2 2025, down from 218 in Q1 2025.
  • Funds reported $953M of Syndax Pharmaceuticals stock for Q2 2025, down 24% quarter-over-quarter.
  • 31 funds opened new Syndax Pharmaceuticals positions in Q2 2025 and 32 closed out, a net change of -1 holder.
  • The largest Syndax Pharmaceuticals buyer in Q2 2025 was BlackRock, an estimated $21.1M added.
  • The largest Syndax Pharmaceuticals seller in Q2 2025 was Citadel Advisors, an estimated $25M sold.

Based on aggregated 13F filings for Q2 2025.