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Syndax Pharmaceuticals

216 hedge funds and large institutions have $953M invested in Syndax Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 31 funds opening new positions, 86 increasing their positions, 66 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

30% more repeat investments, than reductions

Existing positions increased: 86 | Existing positions reduced: 66

15% more call options, than puts

Call options by funds: $14.4M | Put options by funds: $12.5M

0.86% more ownership

Funds ownership: 117.37%118.22% (+0.86%)

1% less funds holding

Funds holding: 218216 (-2)

3% less first-time investments, than exits

New positions opened: 31 | Existing positions closed: 32

24% less capital invested

Capital invested by funds: $1.25B → $953M (-$302M)

30% less funds holding in top 10

Funds holding in top 10: 107 (-3)

Holders
216
Holders Change
-2
Holders Change %
-0.92%
% of All Funds
2.84%
Holding in Top 10
7
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-30%
% of All Funds
0.09%
New
31
Increased
86
Reduced
66
Closed
32
Calls
$14.4M
Puts
$12.5M
Net Calls
+$1.84M
Net Calls Change
-$8.34M
Name Holding Trade Value Shares
Change
Change in
Stake
PD
176
Point72 (DIFC)
United Arab Emirates
$40.5K +$47.6K +4,327 New
Mirae Asset Global Investments
177
Mirae Asset Global Investments
South Korea
$31.1K +$5.15K +468 +16%
AB
178
Amalgamated Bank
New York
$26K
GFM
179
GF Fund Management
China
$20.5K
Walleye Trading
180
Walleye Trading
New York
$18.2K +$21.4K +1,940 New
Osaic Holdings
181
Osaic Holdings
Arizona
$17.6K -$5.76K -523 -22%
CIAM
182
Caitong International Asset Management
Hong Kong
$12K +$11.8K +1,068 +511%
Nisa Investment Advisors
183
Nisa Investment Advisors
Missouri
$10.3K +$2.44K +222 +25%
LFG
184
Larson Financial Group
Missouri
$9.37K -$264 -24 -2%
MCM
185
MAI Capital Management
Ohio
$9.37K
TC
186
Truvestments Capital
Florida
$7.74K
VCM
187
Versant Capital Management
Arizona
$7.7K +$9.05K +822 New
Optiver Holding
188
Optiver Holding
Netherlands
$4.79K +$2.64K +240 +89%
PNC Financial Services Group
189
PNC Financial Services Group
Pennsylvania
$4.72K -$18.1K -1,640 -76%
PS
190
Principal Securities
Iowa
$3.75K +$4.4K +400 New
SCM
191
Sterling Capital Management
North Carolina
$3.23K +$2.87K +261 +311%
Daiwa Securities Group
192
Daiwa Securities Group
Japan
$3K
GRP
193
Global Retirement Partners
California
$2.95K +$3.47K +315 New
Jones Financial Companies
194
Jones Financial Companies
Missouri
$2.49K +$3.03K +275 New
BIG
195
Brooklyn Investment Group
New York
$2.44K +$2.74K +249 +2,264%
AF
196
Allworth Financial
California
$2.25K +$2.27K +206 +606%
SPIA
197
Steward Partners Investment Advisory
New York
$2.16K
WTA
198
Washington Trust Advisors
Massachusetts
$1.96K
AAP
199
Arax Advisory Partners
Colorado
$1.94K +$2.28K +207 New
SS
200
SBI Securities
Japan
$1.9K +$22 +2 +1%

SNDX Hedge Fund Activity: Q2 2025 in Review

216 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Syndax Pharmaceuticals (SNDX) for Q2 2025, worth a combined $953M — down 24% from $1.25B a quarter earlier.

Sellers outnumbered buyers: 32 funds closed out of SNDX and 31 opened new positions — a net loss of 1 holder — while 66 trimmed existing stakes and 86 added.

The largest buyer was BlackRock, adding an estimated $21.1M. The largest seller was Citadel Advisors, cutting an estimated $25M.

  • 216 institutional investors held Syndax Pharmaceuticals (SNDX) as of Q2 2025, down from 218 in Q1 2025.
  • Funds reported $953M of Syndax Pharmaceuticals stock for Q2 2025, down 24% quarter-over-quarter.
  • 31 funds opened new Syndax Pharmaceuticals positions in Q2 2025 and 32 closed out, a net change of -1 holder.
  • The largest Syndax Pharmaceuticals buyer in Q2 2025 was BlackRock, an estimated $21.1M added.
  • The largest Syndax Pharmaceuticals seller in Q2 2025 was Citadel Advisors, an estimated $25M sold.

Based on aggregated 13F filings for Q2 2025.