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Syndax Pharmaceuticals

216 hedge funds and large institutions have $953M invested in Syndax Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 31 funds opening new positions, 86 increasing their positions, 66 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

30% more repeat investments, than reductions

Existing positions increased: 86 | Existing positions reduced: 66

15% more call options, than puts

Call options by funds: $14.4M | Put options by funds: $12.5M

0.86% more ownership

Funds ownership: 117.37%118.22% (+0.86%)

1% less funds holding

Funds holding: 218216 (-2)

3% less first-time investments, than exits

New positions opened: 31 | Existing positions closed: 32

24% less capital invested

Capital invested by funds: $1.25B → $953M (-$302M)

30% less funds holding in top 10

Funds holding in top 10: 107 (-3)

Holders
216
Holders Change
-2
Holders Change %
-0.92%
% of All Funds
2.84%
Holding in Top 10
7
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-30%
% of All Funds
0.09%
New
31
Increased
86
Reduced
66
Closed
32
Calls
$14.4M
Puts
$12.5M
Net Calls
+$1.84M
Net Calls Change
-$8.34M
Name Holding Trade Value Shares
Change
Change in
Stake
Creative Planning
151
Creative Planning
Kansas
$145K -$287K -26,082 -63%
DS
152
DRW Securities
Illinois
$132K +$156K +14,135 New
EFM
153
E Fund Management
China
$131K -$22K -1,998 -12%
Public Employees Retirement Association of Colorado
154
Public Employees Retirement Association of Colorado
Colorado
$129K
SEI Investments
155
SEI Investments
Pennsylvania
$127K -$126K -11,419 -46%
IC
156
IEQ Capital
California
$123K -$507K -46,050 -78%
AI
157
Atom Investors
Texas
$123K -$486K -44,170 -77%
GC
158
Guggenheim Capital
Illinois
$119K +$2.84K +258 +2%
Pictet Asset Management
159
Pictet Asset Management
Switzerland
$116K +$136K +12,356 New
OF
160
Optimize Financial
California
$114K -$947 -86 -0.7%
XT
161
XTX Topco
Cayman Islands
$112K -$570K -51,767 -81%
Raymond James Financial
162
Raymond James Financial
Florida
$103K +$121K +10,969 New
CWM
163
CIBC World Markets
New York
$98.3K -$85.1K -7,734 -42%
Prudential Financial
164
Prudential Financial
New Jersey
$96.9K +$114K +10,350 New
FCM
165
Farallon Capital Management
California
$93.7K
ACM
166
ADAR1 Capital Management
Texas
$93.7K +$110K +10,000 New
VIA
167
Virtus Investment Advisers
Connecticut
$82.5K -$37.2K -3,379 -28%
Carson Wealth (CWM LLC)
168
Carson Wealth (CWM LLC)
Nebraska
$82K -$161K -14,613 -63%
TRCT
169
Tower Research Capital (TRC)
New York
$79.4K +$47.4K +4,308 +103%
AIP
170
Ameritas Investment Partners
Nebraska
$73.6K
Canada Life
171
Canada Life
Manitoba, Canada
$67K -$148K -13,480 -65%
Lazard Asset Management
172
Lazard Asset Management
New York
$66K +$78.6K +7,142 New
CIA
173
Cape Investment Advisory
Georgia
$60.2K
KBC Group
174
KBC Group
Belgium
$49K
US Bancorp
175
US Bancorp
Minnesota
$41K -$7.45K -677 -13%

SNDX Hedge Fund Activity: Q2 2025 in Review

216 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Syndax Pharmaceuticals (SNDX) for Q2 2025, worth a combined $953M — down 24% from $1.25B a quarter earlier.

Sellers outnumbered buyers: 32 funds closed out of SNDX and 31 opened new positions — a net loss of 1 holder — while 66 trimmed existing stakes and 86 added.

The largest buyer was BlackRock, adding an estimated $21.1M. The largest seller was Citadel Advisors, cutting an estimated $25M.

  • 216 institutional investors held Syndax Pharmaceuticals (SNDX) as of Q2 2025, down from 218 in Q1 2025.
  • Funds reported $953M of Syndax Pharmaceuticals stock for Q2 2025, down 24% quarter-over-quarter.
  • 31 funds opened new Syndax Pharmaceuticals positions in Q2 2025 and 32 closed out, a net change of -1 holder.
  • The largest Syndax Pharmaceuticals buyer in Q2 2025 was BlackRock, an estimated $21.1M added.
  • The largest Syndax Pharmaceuticals seller in Q2 2025 was Citadel Advisors, an estimated $25M sold.

Based on aggregated 13F filings for Q2 2025.