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Syndax Pharmaceuticals

229 hedge funds and large institutions have $2.1B invested in Syndax Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 33 funds opening new positions, 83 increasing their positions, 80 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

108% more call options, than puts

Call options by funds: $30M | Put options by funds: $14.4M

35% more capital invested

Capital invested by funds: $1.56B → $2.1B (+$543M)

22% more first-time investments, than exits

New positions opened: 33 | Existing positions closed: 27

10% more funds holding in top 10

Funds holding in top 10: 1011 (+1)

4% more repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 80

1% more funds holding

Funds holding: 227229 (+2)

2.44% less ownership

Funds ownership: 117.38%114.94% (-2.4%)

Holders
229
Holders Change
+2
Holders Change %
+0.88%
% of All Funds
2.78%
Holding in Top 10
11
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+10%
% of All Funds
0.13%
New
33
Increased
83
Reduced
80
Closed
27
Calls
$30M
Puts
$14.4M
Net Calls
+$15.6M
Net Calls Change
+$3.08M
Name Holding Trade Value Shares
Change
Change in
Stake
EGM
126
Engineers Gate Manager
New York
$552K -$2.67M -153,101 -85%
Simplex Trading
127
Simplex Trading
Illinois
$539K +$448K +25,660 New
Manulife (Manufacturers Life Insurance)
128
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$535K -$57.6K -3,303 -11%
New York State Common Retirement Fund
129
New York State Common Retirement Fund
New York
$533K
Royal Bank of Canada
130
Royal Bank of Canada
Ontario, Canada
$532K -$3.54M -202,660 -89%
Envestnet Asset Management
131
Envestnet Asset Management
Illinois
$521K +$433K +24,806 New
PR
132
PSP Research
Pennsylvania
$519K +$431K +24,716 New
Creative Planning
133
Creative Planning
Kansas
$519K +$118K +6,741 +38%
Walleye Capital
134
Walleye Capital
New York
$509K -$4.77M -273,453 -92%
Citigroup
135
Citigroup
New York
$499K +$211K +12,071 +103%
PFSRSONJ
136
Police & Firemen's Retirement System of New Jersey
New Jersey
$491K -$10.4K -597 -2%
Cetera Investment Advisers
137
Cetera Investment Advisers
Illinois
$486K +$403K +23,116 New
HSBC Holdings
138
HSBC Holdings
United Kingdom
$482K -$590K -33,793 -60%
ASRS
139
Arizona State Retirement System
Arizona
$479K -$23.5K -1,345 -6%
PRTG
140
Post Resch Tallon Group
New York
$479K -$52.3K -3,000 -12%
GCP
141
GSA Capital Partners
United Kingdom
$473K +$98K +5,615 +33%
II
142
Inspire Investing
Idaho
$465K -$117K -6,691 -23%
Zurich Cantonal Bank
143
Zurich Cantonal Bank
Switzerland
$432K
QCM
144
Quantinno Capital Management
New York
$427K +$355K +20,339 New
Squarepoint
145
Squarepoint
New York
$416K -$274K -15,705 -44%
BC
146
Bridgefront Capital
Texas
$415K -$36.6K -2,096 -10%
Wealth Enhancement Advisory Services
147
Wealth Enhancement Advisory Services
Minnesota
$411K +$128K +7,310 +57%
ProShare Advisors
148
ProShare Advisors
Maryland
$407K +$30.5K +1,749 +10%
State Board of Administration of Florida Retirement System
149
State Board of Administration of Florida Retirement System
Florida
$399K
HighTower Advisors
150
HighTower Advisors
Illinois
$398K +$26.5K +1,517 +9%