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Syndax Pharmaceuticals

216 hedge funds and large institutions have $953M invested in Syndax Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 31 funds opening new positions, 86 increasing their positions, 66 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

30% more repeat investments, than reductions

Existing positions increased: 86 | Existing positions reduced: 66

15% more call options, than puts

Call options by funds: $14.4M | Put options by funds: $12.5M

0.86% more ownership

Funds ownership: 117.37%118.22% (+0.86%)

1% less funds holding

Funds holding: 218216 (-2)

3% less first-time investments, than exits

New positions opened: 31 | Existing positions closed: 32

24% less capital invested

Capital invested by funds: $1.25B → $953M (-$302M)

30% less funds holding in top 10

Funds holding in top 10: 107 (-3)

Holders
216
Holders Change
-2
Holders Change %
-0.92%
% of All Funds
2.84%
Holding in Top 10
7
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-30%
% of All Funds
0.09%
New
31
Increased
86
Reduced
66
Closed
32
Calls
$14.4M
Puts
$12.5M
Net Calls
+$1.84M
Net Calls Change
-$8.34M
Name Holding Trade Value Shares
Change
Change in
Stake
HWAM
126
Hennion & Walsh Asset Management
New Jersey
$301K +$354K +32,185 New
DnB Asset Management
127
DnB Asset Management
Norway
$275K +$76.9K +6,984 +31%
BHCM
128
Brevan Howard Capital Management
Jersey
$264K -$353K -32,110 -53%
NRD
129
Nebula Research & Development
New York
$255K -$499K -45,327 -62%
DekaBank Deutsche Girozentrale
130
DekaBank Deutsche Girozentrale
Germany
$251K
PA
131
Profund Advisors
Maryland
$249K -$97.3K -8,842 -25%
New York State Common Retirement Fund
132
New York State Common Retirement Fund
New York
$238K
ASRS
133
Arizona State Retirement System
Arizona
$235K +$33.9K +3,080 +14%
SAM
134
Simplify Asset Management
Nevada
$235K -$1.35M -122,736 -83%
Jacobs Levy Equity Management
135
Jacobs Levy Equity Management
New Jersey
$220K +$259K +23,530 New
Teacher Retirement System of Texas
136
Teacher Retirement System of Texas
Texas
$217K +$27.1K +2,458 +12%
JFG
137
Jefferies Financial Group
New York
$215K +$253K +23,000 New
BPC
138
Bryce Point Capital
New York
$198K +$232K +21,109 New
A
139
AlphaQuest
New York
$196K -$202K -18,370 -47%
ProShare Advisors
140
ProShare Advisors
Maryland
$194K -$10.5K -951 -4%
Zurich Cantonal Bank
141
Zurich Cantonal Bank
Switzerland
$192K +$80.1K +7,281 +55%
Simplex Trading
142
Simplex Trading
Illinois
$186K +$201K +18,264 +1,102%
State Board of Administration of Florida Retirement System
143
State Board of Administration of Florida Retirement System
Florida
$178K
FRM
144
Fox Run Management
Connecticut
$172K +$202K +18,363 New
PFSRSONJ
145
Police & Firemen's Retirement System of New Jersey
New Jersey
$167K
CC
146
Corton Capital
Ontario, Canada
$167K +$197K +17,856 New
GCP
147
GSA Capital Partners
United Kingdom
$163K -$769K -69,854 -80%
CUAMC
148
China Universal Asset Management Company
China
$162K +$1.77K +161 +0.9%
KK
149
KLP Kapitalforvaltning
Norway
$155K
FGP
150
Freestone Grove Partners
California
$145K -$16.6K -1,507 -9%

SNDX Hedge Fund Activity: Q2 2025 in Review

216 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Syndax Pharmaceuticals (SNDX) for Q2 2025, worth a combined $953M — down 24% from $1.25B a quarter earlier.

Sellers outnumbered buyers: 32 funds closed out of SNDX and 31 opened new positions — a net loss of 1 holder — while 66 trimmed existing stakes and 86 added.

The largest buyer was BlackRock, adding an estimated $21.1M. The largest seller was Citadel Advisors, cutting an estimated $25M.

  • 216 institutional investors held Syndax Pharmaceuticals (SNDX) as of Q2 2025, down from 218 in Q1 2025.
  • Funds reported $953M of Syndax Pharmaceuticals stock for Q2 2025, down 24% quarter-over-quarter.
  • 31 funds opened new Syndax Pharmaceuticals positions in Q2 2025 and 32 closed out, a net change of -1 holder.
  • The largest Syndax Pharmaceuticals buyer in Q2 2025 was BlackRock, an estimated $21.1M added.
  • The largest Syndax Pharmaceuticals seller in Q2 2025 was Citadel Advisors, an estimated $25M sold.

Based on aggregated 13F filings for Q2 2025.