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Syndax Pharmaceuticals

216 hedge funds and large institutions have $953M invested in Syndax Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 31 funds opening new positions, 86 increasing their positions, 66 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

30% more repeat investments, than reductions

Existing positions increased: 86 | Existing positions reduced: 66

15% more call options, than puts

Call options by funds: $14.4M | Put options by funds: $12.5M

0.86% more ownership

Funds ownership: 117.37%118.22% (+0.86%)

1% less funds holding

Funds holding: 218216 (-2)

3% less first-time investments, than exits

New positions opened: 31 | Existing positions closed: 32

24% less capital invested

Capital invested by funds: $1.25B → $953M (-$302M)

30% less funds holding in top 10

Funds holding in top 10: 107 (-3)

Holders
216
Holders Change
-2
Holders Change %
-0.92%
% of All Funds
2.84%
Holding in Top 10
7
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-30%
% of All Funds
0.09%
New
31
Increased
86
Reduced
66
Closed
32
Calls
$14.4M
Puts
$12.5M
Net Calls
+$1.84M
Net Calls Change
-$8.34M
Name Holding Trade Value Shares
Change
Change in
Stake
VOYA Investment Management
101
VOYA Investment Management
Georgia
$851K +$492K +44,666 +97%
UOC
102
UBS O'Connor
Illinois
$847K +$341K +31,003 +52%
PCM
103
Prelude Capital Management
New York
$841K -$20.7K -1,884 -2%
Stifel Financial
104
Stifel Financial
Missouri
$834K +$162K +14,750 +20%
NIM
105
NEOS Investment Management
Connecticut
$808K +$717K +65,132 +308%
TE
106
Tema ETFs
New York
$808K +$717K +65,132 +308%
Legal & General Group
107
Legal & General Group
United Kingdom
$792K +$43.3K +3,937 +5%
T. Rowe Price Associates
108
T. Rowe Price Associates
Maryland
$706K +$102K +9,290 +14%
PF
109
Phoenix Financial
Israel
$701K +$825K +74,963 New
California State Teachers Retirement System (CalSTRS)
110
California State Teachers Retirement System (CalSTRS)
California
$674K
Deutsche Bank
111
Deutsche Bank
Germany
$607K -$1.54M -139,961 -68%
SAM
112
Sectoral Asset Management
Quebec, Canada
$593K +$697K +63,300 New
QL
113
Quarry LP
New York
$553K +$627K +57,000 +2,850%
LPC
114
Lion Point Capital
New York
$515K
Tudor Investment Corp
115
Tudor Investment Corp
Connecticut
$497K -$153K -13,932 -21%
Mirae Asset Global ETFs Holdings
116
Mirae Asset Global ETFs Holdings
Hong Kong
$493K -$44K -3,997 -7%
MIM
117
MetLife Investment Management
New Jersey
$466K
CCIA
118
Campbell & Co Investment Adviser
Maryland
$439K +$515K +46,829 New
IIM
119
INTECH Investment Management
Florida
$428K -$109K -9,911 -18%
Manulife (Manufacturers Life Insurance)
120
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$413K +$27.3K +2,479 +6%
II
121
Inspire Investing
Idaho
$402K +$165K +15,025 +54%
Janus Henderson Group
122
Janus Henderson Group
United Kingdom
$368K
Squarepoint
123
Squarepoint
New York
$349K +$410K +37,257 New
CC
124
Clearline Capital
New York
$320K
Wellington Management Group
125
Wellington Management Group
Massachusetts
$319K -$20.7K -1,877 -5%

SNDX Hedge Fund Activity: Q2 2025 in Review

216 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Syndax Pharmaceuticals (SNDX) for Q2 2025, worth a combined $953M — down 24% from $1.25B a quarter earlier.

Sellers outnumbered buyers: 32 funds closed out of SNDX and 31 opened new positions — a net loss of 1 holder — while 66 trimmed existing stakes and 86 added.

The largest buyer was BlackRock, adding an estimated $21.1M. The largest seller was Citadel Advisors, cutting an estimated $25M.

  • 216 institutional investors held Syndax Pharmaceuticals (SNDX) as of Q2 2025, down from 218 in Q1 2025.
  • Funds reported $953M of Syndax Pharmaceuticals stock for Q2 2025, down 24% quarter-over-quarter.
  • 31 funds opened new Syndax Pharmaceuticals positions in Q2 2025 and 32 closed out, a net change of -1 holder.
  • The largest Syndax Pharmaceuticals buyer in Q2 2025 was BlackRock, an estimated $21.1M added.
  • The largest Syndax Pharmaceuticals seller in Q2 2025 was Citadel Advisors, an estimated $25M sold.

Based on aggregated 13F filings for Q2 2025.