We are live on ! Find out more
SNDX icon

Syndax Pharmaceuticals

216 hedge funds and large institutions have $953M invested in Syndax Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 31 funds opening new positions, 86 increasing their positions, 66 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

30% more repeat investments, than reductions

Existing positions increased: 86 | Existing positions reduced: 66

15% more call options, than puts

Call options by funds: $14.4M | Put options by funds: $12.5M

0.86% more ownership

Funds ownership: 117.37%118.22% (+0.86%)

1% less funds holding

Funds holding: 218216 (-2)

3% less first-time investments, than exits

New positions opened: 31 | Existing positions closed: 32

24% less capital invested

Capital invested by funds: $1.25B → $953M (-$302M)

30% less funds holding in top 10

Funds holding in top 10: 107 (-3)

Holders
216
Holders Change
-2
Holders Change %
-0.92%
% of All Funds
2.84%
Holding in Top 10
7
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-30%
% of All Funds
0.09%
New
31
Increased
86
Reduced
66
Closed
32
Calls
$14.4M
Puts
$12.5M
Net Calls
+$1.84M
Net Calls Change
-$8.34M
Name Holding Trade Value Shares
Change
Change in
Stake
Jane Street
76
Jane Street
New York
$1.57M +$829K +75,277 +82%
Swiss National Bank
77
Swiss National Bank
Switzerland
$1.54M +$164K +14,900 +10%
Fidelity Investments
78
Fidelity Investments
Massachusetts
$1.51M +$426K +38,660 +32%
DFCM
79
Dark Forest Capital Management
Puerto Rico
$1.5M +$1.33M +121,118 +309%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
80
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$1.45M -$1.05M -95,000 -38%
Wells Fargo
81
Wells Fargo
California
$1.45M +$1.23M +111,446 +259%
APM
82
Avidity Partners Management
Texas
$1.4M -$8.53M -775,000 -84%
State of Wisconsin Investment Board
83
State of Wisconsin Investment Board
Wisconsin
$1.32M +$848K +77,006 +120%
BFM
84
Boothbay Fund Management
New York
$1.21M +$1.42M +128,845 New
RhumbLine Advisers
85
RhumbLine Advisers
Massachusetts
$1.21M +$87.2K +7,922 +7%
HF
86
HRT Financial
New York
$1.19M -$197K -17,923 -12%
Russell Investments Group
87
Russell Investments Group
United Kingdom
$1.18M +$94.1K +8,545 +7%
Balyasny Asset Management
88
Balyasny Asset Management
Illinois
$1.18M -$18.6M -1,690,864 -93%
Rafferty Asset Management
89
Rafferty Asset Management
New York
$1.18M -$501K -45,496 -27%
Verition Fund Management
90
Verition Fund Management
Connecticut
$1.17M +$994K +90,308 +258%
Schroder Investment Management Group
91
Schroder Investment Management Group
United Kingdom
$1.14M +$711K +64,598 +112%
AllianceBernstein
92
AllianceBernstein
Tennessee
$1.1M -$562K -51,035 -30%
TC
93
TwinBeech Capital
New York
$1.06M -$1.57M -143,038 -56%
Citigroup
94
Citigroup
New York
$1.05M -$978K -88,898 -44%
YLHM
95
Yelin Lapidot Holdings Management
Israel
$1.01M
Invesco
96
Invesco
Georgia
$985K +$312K +28,309 +37%
HSBC Holdings
97
HSBC Holdings
United Kingdom
$966K +$622K +56,512 +112%
PAMP
98
Polar Asset Management Partners
Ontario, Canada
$909K -$105K -9,515 -9%
Ameriprise
99
Ameriprise
Minnesota
$905K +$687K +62,446 +182%
SCM
100
Stonepine Capital Management
Oregon
$870K +$1.02M +92,900 New

SNDX Hedge Fund Activity: Q2 2025 in Review

216 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Syndax Pharmaceuticals (SNDX) for Q2 2025, worth a combined $953M — down 24% from $1.25B a quarter earlier.

Sellers outnumbered buyers: 32 funds closed out of SNDX and 31 opened new positions — a net loss of 1 holder — while 66 trimmed existing stakes and 86 added.

The largest buyer was BlackRock, adding an estimated $21.1M. The largest seller was Citadel Advisors, cutting an estimated $25M.

  • 216 institutional investors held Syndax Pharmaceuticals (SNDX) as of Q2 2025, down from 218 in Q1 2025.
  • Funds reported $953M of Syndax Pharmaceuticals stock for Q2 2025, down 24% quarter-over-quarter.
  • 31 funds opened new Syndax Pharmaceuticals positions in Q2 2025 and 32 closed out, a net change of -1 holder.
  • The largest Syndax Pharmaceuticals buyer in Q2 2025 was BlackRock, an estimated $21.1M added.
  • The largest Syndax Pharmaceuticals seller in Q2 2025 was Citadel Advisors, an estimated $25M sold.

Based on aggregated 13F filings for Q2 2025.