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Syndax Pharmaceuticals

218 hedge funds and large institutions have $1.25B invested in Syndax Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 31 funds opening new positions, 88 increasing their positions, 63 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

129% more call options, than puts

Call options by funds: $18.1M | Put options by funds: $7.88M

40% more repeat investments, than reductions

Existing positions increased: 88 | Existing positions reduced: 63

25% more funds holding in top 10

Funds holding in top 10: 810 (+2)

19% more first-time investments, than exits

New positions opened: 31 | Existing positions closed: 26

2.52% more ownership

Funds ownership: 114.85%117.37% (+2.5%)

1% more funds holding

Funds holding: 215218 (+3)

3% less capital invested

Capital invested by funds: $1.3B → $1.25B (-$41.1M)

Holders
218
Holders Change
+3
Holders Change %
+1.4%
% of All Funds
2.92%
Holding in Top 10
10
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+25%
% of All Funds
0.13%
New
31
Increased
88
Reduced
63
Closed
26
Calls
$18.1M
Puts
$7.88M
Net Calls
+$10.2M
Net Calls Change
-$2.9M
Name Holding Trade Value Shares
Change
Change in
Stake
PAI
51
Palo Alto Investors
California
$5.46M +$553K +39,174 +10%
RPAM
52
Rhenman & Partners Asset Management
Sweden
$5.32M +$2.84M +201,000 +87%
Millennium Management
53
Millennium Management
New York
$5.27M -$2.23M -158,158 -27%
TI
54
Trexquant Investment
Connecticut
$4.75M -$1.2M -85,029 -18%
AQR Capital Management
55
AQR Capital Management
Connecticut
$4.64M +$4.4M +312,231 +479%
EAM
56
Exome Asset Management
New York
$4.14M +$258K +18,298 +6%
Susquehanna International Group
57
Susquehanna International Group
Pennsylvania
$4.05M +$2.85M +202,349 +159%
Walleye Capital
58
Walleye Capital
New York
$4.02M -$531K -37,616 -10%
ECM
59
ExodusPoint Capital Management
New York
$3.86M +$2.34M +165,839 +112%
TC
60
TwinBeech Capital
New York
$3.14M -$1.41M -100,068 -28%
Hudson Bay Capital Management
61
Hudson Bay Capital Management
Connecticut
$3.07M -$1.21M -86,000 -26%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
62
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$3.07M -$28.2K -2,000 -0.8%
Bank of New York Mellon
63
Bank of New York Mellon
New York
$2.82M +$77.5K +5,497 +2%
N
64
Nuveen
North Carolina
$2.75M -$2.96M -209,905 -48%
BNP Paribas Financial Markets
65
BNP Paribas Financial Markets
France
$2.67M -$596K -42,252 -16%
ZP
66
Zimmer Partners
New York
$2.62M +$3.01M +213,159 New
Deutsche Bank
67
Deutsche Bank
Germany
$2.52M +$1.62M +114,828 +128%
UBS AM
68
UBS AM
Illinois
$2.47M +$432K +30,596 +18%
Citigroup
69
Citigroup
New York
$2.46M +$793K +56,198 +39%
TCM
70
Tang Capital Management
California
$2.46M +$1.41M +100,000 +100%
VIG
71
Vienna Insurance Group
Poland
$2.46M +$2.82M +200,000 New
Barclays
72
Barclays
United Kingdom
$2.46M +$55.5K +3,938 +2%
PE
73
Point72 Europe
United Kingdom
$2.27M +$2.6M +184,683 New
PBM
74
Propel Bio Management
California
$2.25M
CM
75
Caption Management
Oklahoma
$2.23M -$462K -32,767 -15%

SNDX Hedge Fund Activity: Q1 2025 in Review

218 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Syndax Pharmaceuticals (SNDX) for Q1 2025, worth a combined $1.25B — down 3.2% from $1.3B a quarter earlier.

Buyers outnumbered sellers: 31 funds opened new SNDX positions and 26 closed out — a net gain of 5 holders — while 88 added to existing stakes and 63 trimmed.

The largest buyer was Eversept Partners, adding an estimated $54.6M. The largest seller was Wellington Management Group, cutting an estimated $59.2M.

  • 218 institutional investors held Syndax Pharmaceuticals (SNDX) as of Q1 2025, up from 215 in Q4 2024.
  • Funds reported $1.25B of Syndax Pharmaceuticals stock for Q1 2025, down 3.2% quarter-over-quarter.
  • 31 funds opened new Syndax Pharmaceuticals positions in Q1 2025 and 26 closed out, a net change of +5 holders.
  • The largest Syndax Pharmaceuticals buyer in Q1 2025 was Eversept Partners, an estimated $54.6M added.
  • The largest Syndax Pharmaceuticals seller in Q1 2025 was Wellington Management Group, an estimated $59.2M sold.

Based on aggregated 13F filings for Q1 2025.