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Syndax Pharmaceuticals

229 hedge funds and large institutions have $2.1B invested in Syndax Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 33 funds opening new positions, 83 increasing their positions, 80 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

108% more call options, than puts

Call options by funds: $30M | Put options by funds: $14.4M

35% more capital invested

Capital invested by funds: $1.56B → $2.1B (+$543M)

22% more first-time investments, than exits

New positions opened: 33 | Existing positions closed: 27

10% more funds holding in top 10

Funds holding in top 10: 1011 (+1)

4% more repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 80

1% more funds holding

Funds holding: 227229 (+2)

2.44% less ownership

Funds ownership: 117.38%114.94% (-2.4%)

Holders
229
Holders Change
+2
Holders Change %
+0.88%
% of All Funds
2.78%
Holding in Top 10
11
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+10%
% of All Funds
0.13%
New
33
Increased
83
Reduced
80
Closed
27
Calls
$30M
Puts
$14.4M
Net Calls
+$15.6M
Net Calls Change
+$3.08M
Name Holding Trade Value Shares
Change
Change in
Stake
Bank of New York Mellon
26
Bank of New York Mellon
New York
$23M +$730K +41,816 +4%
Morgan Stanley
27
Morgan Stanley
New York
$22.6M -$2.16M -123,795 -10%
AG
28
Algert Global
California
$19.5M -$46.7K -2,678 -0.3%
AQR Capital Management
29
AQR Capital Management
Connecticut
$19.5M +$6.42M +367,898 +66%
CS
30
Candriam SCA
Luxembourg
$19.4M
PAI
31
Palo Alto Investors
California
$16.7M +$2.44M +139,577 +21%
SFM
32
Sphera Funds Management
Israel
$16M +$6.54M +374,847 +97%
Jane Street
33
Jane Street
New York
$15.7M +$186K +10,654 +1%
Northern Trust
34
Northern Trust
Illinois
$15.3M -$833K -47,765 -6%
Charles Schwab
35
Charles Schwab
California
$15.3M +$146K +8,390 +1%
ACA
36
Apis Capital Advisors
New York
$15.2M +$1.5M +86,000 +13%
UBS Group
37
UBS Group
Switzerland
$15M -$16.7M -958,294 -57%
Qube Research & Technologies (QRT)
38
Qube Research & Technologies (QRT)
United Kingdom
$14.5M -$16.7M -956,707 -58%
PM
39
Prosight Management
Texas
$14M -$5.9M -338,400 -34%
SCM
40
Silverarc Capital Management
Massachusetts
$13.5M +$3.13M +179,191 +39%
Two Sigma Advisers
41
Two Sigma Advisers
New York
$13.3M +$4.36M +249,700 +65%
PHP
42
Parkman Healthcare Partners
Connecticut
$12.1M -$4.76M -272,876 -32%
ECM
43
ExodusPoint Capital Management
New York
$11.7M +$8.41M +482,297 +666%
Renaissance Technologies
44
Renaissance Technologies
New York
$11.4M -$5.51M -315,700 -37%
BHCM
45
Brevan Howard Capital Management
Jersey
$10.8M +$6.81M +390,554 +314%
RPAM
46
Rhenman & Partners Asset Management
Sweden
$10.2M -$1.52M -87,000 -15%
DMKJ
47
David M. Knott Jr
$8.72M -$227K -13,000 -3%
JP Morgan Chase
48
JP Morgan Chase
New York
$7.95M +$2.17M +124,654 +49%
Aberdeen Group
49
Aberdeen Group
United Kingdom
$7.83M
GIM
50
Granahan Investment Management
Massachusetts
$7.71M -$515K -29,543 -7%