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Syndax Pharmaceuticals

216 hedge funds and large institutions have $953M invested in Syndax Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 31 funds opening new positions, 86 increasing their positions, 66 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

30% more repeat investments, than reductions

Existing positions increased: 86 | Existing positions reduced: 66

15% more call options, than puts

Call options by funds: $14.4M | Put options by funds: $12.5M

0.86% more ownership

Funds ownership: 117.37%118.22% (+0.86%)

1% less funds holding

Funds holding: 218216 (-2)

3% less first-time investments, than exits

New positions opened: 31 | Existing positions closed: 32

24% less capital invested

Capital invested by funds: $1.25B → $953M (-$302M)

30% less funds holding in top 10

Funds holding in top 10: 107 (-3)

Holders
216
Holders Change
-2
Holders Change %
-0.92%
% of All Funds
2.84%
Holding in Top 10
7
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-30%
% of All Funds
0.09%
New
31
Increased
86
Reduced
66
Closed
32
Calls
$14.4M
Puts
$12.5M
Net Calls
+$1.84M
Net Calls Change
-$8.34M
Name Holding Trade Value Shares
Change
Change in
Stake
CAU
226
Caxton Associates (UK)
-$257K -20,945 Closed
SPC
227
Sigma Planning Corp
Michigan
-$209K -16,985 Closed
Universal-Beteiligungs- und Servicegesellschaft
228
Universal-Beteiligungs- und Servicegesellschaft
Germany
-$179K -14,560 Closed
SA
229
Sanctuary Advisors
Indiana
-$169K -13,779 Closed
Wealth Enhancement Advisory Services
230
Wealth Enhancement Advisory Services
Minnesota
-$162K -13,172 Closed
MF
231
Magnetar Financial
Illinois
-$132K -10,717 Closed
MFIM
232
Mesirow Financial Investment Management
Illinois
-$115K -10,242 Closed
Victory Capital Management
233
Victory Capital Management
Texas
-$125K -10,148 Closed
ETC
234
Exchange Traded Concepts
Oklahoma
-$120K -9,769 Closed
MIA
235
MeadowBrook Investment Advisors
Michigan
-$18.4K -1,500 Closed
PWMG
236
Private Wealth Management Group
New Jersey
-$3.27K -266 Closed
HNB
237
Huntington National Bank
Ohio
-$3.11K -253 Closed
GWM
238
Geneos Wealth Management
Colorado
-$2.76K -225 Closed
QCG
239
Quadrant Capital Group
Ohio
-$2.38K -194 Closed
ACM
240
Aster Capital Management
United Arab Emirates
-$2.61K -167 Closed
CCM
241
Coldstream Capital Management
Washington
-$579 -47 Closed
PFBT
242
Parkside Financial Bank & Trust
Missouri
-$492 -40 Closed
CAWM
243
Capital A Wealth Management
Pennsylvania
-$369 -30 Closed
SC
244
Stephens Consulting
Michigan
-$369 -30 Closed
SW
245
SVB Wealth
Massachusetts
-$332 -27 Closed
WA
246
WPG Advisers
Maryland
-$135 -11 Closed
C
247
Covestor
United Kingdom
+$308 +28 +311%

SNDX Hedge Fund Activity: Q2 2025 in Review

216 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Syndax Pharmaceuticals (SNDX) for Q2 2025, worth a combined $953M — down 24% from $1.25B a quarter earlier.

Sellers outnumbered buyers: 32 funds closed out of SNDX and 31 opened new positions — a net loss of 1 holder — while 66 trimmed existing stakes and 86 added.

The largest buyer was BlackRock, adding an estimated $21.1M. The largest seller was Citadel Advisors, cutting an estimated $25M.

  • 216 institutional investors held Syndax Pharmaceuticals (SNDX) as of Q2 2025, down from 218 in Q1 2025.
  • Funds reported $953M of Syndax Pharmaceuticals stock for Q2 2025, down 24% quarter-over-quarter.
  • 31 funds opened new Syndax Pharmaceuticals positions in Q2 2025 and 32 closed out, a net change of -1 holder.
  • The largest Syndax Pharmaceuticals buyer in Q2 2025 was BlackRock, an estimated $21.1M added.
  • The largest Syndax Pharmaceuticals seller in Q2 2025 was Citadel Advisors, an estimated $25M sold.

Based on aggregated 13F filings for Q2 2025.