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SMLR

Semler Scientific
SMLR

Delisted

SMLR was delisted on the 15th of January, 2026.

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49 hedge funds and large institutions have $301M invested in Semler Scientific in 2021 Q3 according to their latest regulatory filings, with 44 funds opening new positions, 1 increasing their positions, 3 reducing their positions, and 0 closing their positions.

New
Increased
Maintained
Reduced
Closed

880% more funds holding

Funds holding: 5 → 49 (+44)

299% more capital invested

Capital invested by funds: $75.5M → $301M (+$226M)

35.68% more ownership

Funds ownership: 0% → 35.68% (+36%)

67% less repeat investments, than reductions

Existing positions increased: 1 | Existing positions reduced: 3

Holders
49
Holders Change
+44
Holders Change %
+880%
% of All Funds
0.86%
Holding in Top 10
4
Holding in Top 10 Change
+4
Holding in Top 10 Change %
% of All Funds
0.07%
New
44
Increased
1
Reduced
3
Closed
–
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
OM
Opaleye Management
Massachusetts
+$28.5M
2
PCA
Prospect Capital Advisors
California
+$25.2M
3
Fidelity Investments
Fidelity Investments
Massachusetts
+$24M
4
AG
Aravt Global
New York
+$19.8M
5
Goldman Sachs
Goldman Sachs
New York
+$19M

Top Sellers

Rank Fund Capital Flow
1
PWAM
Park West Asset Management
California
-$6.57M
2
JIR
James Investment Research
Ohio
-$260K
3
GGHC
Gilder Gagnon Howe & Co
New York
-$15.8K
Name Holding Trade Value Shares
Change 		Change in
Stake
PWAM
1
Park West Asset Management
California
$69.6M -$6.57M -52,057 -9%
OM
2
Opaleye Management
Massachusetts
$28.2M +$28.5M +225,566 New
PCA
3
Prospect Capital Advisors
California
$25M +$25.2M +199,810 New
Fidelity Investments
4
Fidelity Investments
Massachusetts
$24M +$24M +190,426 New
AG
5
Aravt Global
New York
$19.6M +$19.8M +157,056 New
Goldman Sachs
6
Goldman Sachs
New York
$18.8M +$19M +150,756 New
PAIM
7
Punch & Associates Investment Management
Minnesota
$18.4M +$18.6M +147,339 New
NCM
8
Nantahala Capital Management
Connecticut
$18.2M +$18.4M +145,419 New
PCM
9
Portolan Capital Management
Massachusetts
$10.3M +$10.4M +82,212 New
KLC
10
Kent Lake Capital
Nevada
$7.5M +$7.58M +60,000 New
GGHC
11
Gilder Gagnon Howe & Co
New York
$6.91M -$15.8K -125 -0.2%
IAM
12
Iridian Asset Management
Connecticut
$4.95M +$5M +39,597 New
RA
13
Royce & Associates
New York
$4.83M +$4.85M +38,400 New
ACA
14
Apis Capital Advisors
New York
$4.3M +$4.34M +34,400 New
AIA
15
Avalon Investment & Advisory
Texas
$4.16M +$4.2M +33,230 New
DC
16
Diametric Capital
Massachusetts
$3.78M +$3.82M +30,238 New
Acadian Asset Management
17
Acadian Asset Management
Massachusetts
$3.56M +$3.6M +28,474 New
PHP
18
Parkman Healthcare Partners
Connecticut
$3.13M +$3.16M +24,998 New
CAM
19
Connacht Asset Management
New York
$2.81M +$2.84M +22,463 New
PCM
20
Prelude Capital Management
New York
$2.55M +$2.58M +20,425 New
Manulife (Manufacturers Life Insurance)
21
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$2.5M +$2.53M +20,000 New
GIPM
22
G2 Investment Partners Management
New York
$2.38M +$2.4M +19,035 New
BFM
23
Boothbay Fund Management
New York
$2.35M +$2.38M +18,829 New
CCA
24
Conestoga Capital Advisors
Pennsylvania
$2.24M +$2.26M +17,895 New
JMPWA
25
JP Morgan Private Wealth Advisors
California
$2.13M +$2.15M +17,000 New
1
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SMLR Hedge Fund Activity: Q3 2021 in Review

49 of the 5,712 institutional investors tracked by Wall St. Rank reported a position in Semler Scientific (SMLR) for Q3 2021, worth a combined $301M — up 299% from $75.5M a quarter earlier.

Buyers outnumbered sellers: 44 funds opened new SMLR positions and 0 closed out — a net gain of 44 holders — while 1 added to existing stakes and 3 trimmed.

The largest buyer was Opaleye Management, opening a new position worth an estimated $28.5M. The largest seller was Park West Asset Management, cutting an estimated $6.57M.

  • 49 institutional investors held Semler Scientific (SMLR) as of Q3 2021, up from 5 in Q2 2021.
  • Funds reported $301M of Semler Scientific stock for Q3 2021, up 299% quarter-over-quarter.
  • 44 funds opened new Semler Scientific positions in Q3 2021 and 0 closed out, a net change of +44 holders.
  • The largest Semler Scientific buyer in Q3 2021 was Opaleye Management, an estimated $28.5M added.
  • The largest Semler Scientific seller in Q3 2021 was Park West Asset Management, an estimated $6.57M sold.

Based on aggregated 13F filings for Q3 2021.