We are live on ! Find out more
SERA icon

Sera Prognostics
SERA

57 hedge funds and large institutions have $52.4M invested in Sera Prognostics in 2025 Q4 according to their latest regulatory filings, with 6 funds opening new positions, 15 increasing their positions, 14 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

7% more repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 14

0% more funds holding in top 10

Funds holding in top 10: 1 → 1 (0)

2.32% less ownership

Funds ownership: 49.47% → 47.15% (-2.3%)

6% less capital invested

Capital invested by funds: $55.6M → $52.4M (-$3.21M)

8% less funds holding

Funds holding: 62 → 57 (-5)

25% less first-time investments, than exits

New positions opened: 6 | Existing positions closed: 8

Holders
57
Holders Change
-5
Holders Change %
-8.06%
% of All Funds
0.69%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
6
Increased
15
Reduced
14
Closed
8
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
Corient Private Wealth
Corient Private Wealth
Florida
+$323K
2
Jane Street
Jane Street
New York
+$222K
3
Citadel Advisors
Citadel Advisors
Florida
+$174K
4
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$159K
5
GCP
GSA Capital Partners
United Kingdom
+$136K

Top Sellers

Rank Fund Capital Flow
1
SMH
Sanders Morris Harris
Texas
-$807K
2
WCA
Whetstone Capital Advisors
Kansas
-$557K
3
BL
Balentine LLC
Georgia
-$258K
4
CCWA
CLA (CliftonLarsonAllen) Wealth Advisors
Minnesota
-$241K
5
CAPTRUST Financial Advisors
CAPTRUST Financial Advisors
North Carolina
-$212K
Name Holding Trade Value Shares
Change 		Change in
Stake
BBA
1
Baker Bros. Advisors
New York
$16.2M – – –
WCA
2
Whetstone Capital Advisors
Kansas
$10.2M -$557K -172,658 -5%
Aberdeen Group
3
Aberdeen Group
United Kingdom
$6.73M – – –
VC
4
Vivo Capital
California
$4.87M – – –
Vanguard Group
5
Vanguard Group
Pennsylvania
$3.66M +$71.8K +22,259 +2%
Citadel Advisors
6
Citadel Advisors
Florida
$2.09M +$174K +53,868 +8%
CAPTRUST Financial Advisors
7
CAPTRUST Financial Advisors
North Carolina
$1.58M -$212K -65,570 -11%
Geode Capital Management
8
Geode Capital Management
Massachusetts
$987K +$11.4K +3,524 +1%
AIC
9
AWM Investment Company
New York
$612K – – –
Corient Private Wealth
10
Corient Private Wealth
Florida
$580K +$323K +100,000 +100%
BlackRock
11
BlackRock
New York
$551K +$25.1K +7,774 +4%
State Street
12
State Street
Massachusetts
$368K – – –
Millennium Management
13
Millennium Management
New York
$334K -$45.5K -14,109 -11%
GCP
14
GSA Capital Partners
United Kingdom
$316K +$136K +42,045 +64%
Northern Trust
15
Northern Trust
Illinois
$285K +$26K +8,052 +9%
Morgan Stanley
16
Morgan Stanley
New York
$239K -$9.82K -3,046 -4%
Bank of New York Mellon
17
Bank of New York Mellon
New York
$222K – – –
PWM
18
Perigon Wealth Management
California
$214K – – –
Susquehanna International Group
19
Susquehanna International Group
Pennsylvania
$211K +$159K +49,160 +220%
Jane Street
20
Jane Street
New York
$203K +$222K +68,826 New
RCM
21
Requisite Capital Management
Texas
$164K – – –
TPWM
22
Twelve Points Wealth Management
Massachusetts
$160K – – –
BP
23
Ballentine Partners
Massachusetts
$147K – – –
BCM
24
Bridgeway Capital Management
Texas
$135K – – –
HighTower Advisors
25
HighTower Advisors
Illinois
$125K – – –
1
2 3

SERA Hedge Fund Activity: Q4 2025 in Review

57 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Sera Prognostics (SERA) for Q4 2025, worth a combined $52.4M — down 5.8% from $55.6M a quarter earlier.

Sellers outnumbered buyers: 8 funds closed out of SERA and 6 opened new positions — a net loss of 2 holders — while 14 trimmed existing stakes and 15 added.

The largest buyer was Corient Private Wealth, adding an estimated $323K. The largest seller was Sanders Morris Harris, exiting entirely with an estimated $807K sold.

  • 57 institutional investors held Sera Prognostics (SERA) as of Q4 2025, down from 62 in Q3 2025.
  • Funds reported $52.4M of Sera Prognostics stock for Q4 2025, down 5.8% quarter-over-quarter.
  • 6 funds opened new Sera Prognostics positions in Q4 2025 and 8 closed out, a net change of -2 holders.
  • The largest Sera Prognostics buyer in Q4 2025 was Corient Private Wealth, an estimated $323K added.
  • The largest Sera Prognostics seller in Q4 2025 was Sanders Morris Harris, an estimated $807K sold.

Based on aggregated 13F filings for Q4 2025.