Sera Prognostics
SERA
57 hedge funds and large institutions have $52.4M invested in Sera Prognostics in 2025 Q4 according to their latest regulatory filings, with 6 funds opening new positions, 15 increasing their positions, 14 reducing their positions, and 8 closing their positions.
7% more repeat investments, than reductions
Existing positions increased: 15 | Existing positions reduced: 14
0% more funds holding in top 10
Funds holding in top 10: 1 → 1 (0)
2.32% less ownership
Funds ownership: 49.47% → 47.15% (-2.3%)
6% less capital invested
Capital invested by funds: $55.6M → $52.4M (-$3.21M)
8% less funds holding
Funds holding: 62 → 57 (-5)
25% less first-time investments, than exits
New positions opened: 6 | Existing positions closed: 8
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Corient Private Wealth
Miami,
Florida
|
+$323K |
| 2 |
Jane Street
New York
|
+$222K |
| 3 |
Citadel Advisors
Miami,
Florida
|
+$174K |
| 4 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
+$159K |
| 5 |
GCP
GSA Capital Partners
London,
United Kingdom
|
+$136K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
SMH
Sanders Morris Harris
Houston,
Texas
|
-$807K |
| 2 |
WCA
Whetstone Capital Advisors
Shawnee Mission,
Kansas
|
-$557K |
| 3 |
BL
Balentine LLC
Atlanta,
Georgia
|
-$258K |
| 4 |
CCWA
CLA (CliftonLarsonAllen) Wealth Advisors
Minneapolis,
Minnesota
|
-$241K |
| 5 |
CAPTRUST Financial Advisors
Raleigh,
North Carolina
|
-$212K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
FFO
51
Fortitude Family Office
Scottsdale,
Arizona
| $888 | – | – | – |
|
52
BNP Paribas Financial Markets
Paris,
France
| $696 | – | – | – |
|
53
JP Morgan Chase
New York
| $655 | – | – | – |
|
54
Citigroup
New York
| $590 | +$629 | +195 | +3,900% |
|
55
Nisa Investment Advisors
St. Louis,
Missouri
| $381 | – | – | – |
|
|
SS
56
SBI Securities
Tokyo,
Japan
| $21 | -$3 | -1 | -13% |
|
|
SMH
57
Sanders Morris Harris
Houston,
Texas
| – | -$807K | -263,600 | Closed |
|
|
BL
58
Balentine LLC
Atlanta,
Georgia
| – | -$258K | -84,475 | Closed |
|
|
CCWA
59
CLA (CliftonLarsonAllen) Wealth Advisors
Minneapolis,
Minnesota
| – | -$241K | -78,855 | Closed |
|
|
CG
60
Caprock Group
Boise,
Idaho
| – | -$108K | -33,523 | Closed |
|
|
PCA
61
Pallas Capital Advisors
Braintree,
Massachusetts
| – | -$42K | -13,711 | Closed |
|
|
VPIM
62
Vanguard Personalized Indexing Management
Oakland,
California
| – | -$38.4K | -12,561 | Closed |
|
63
Royal Bank of Canada
Toronto,
Ontario, Canada
| – | -$7.01K | -2,173 | -98% |
|
|
ASN
64
Advisory Services Network
Atlanta,
Georgia
| – | -$58 | -19 | Closed |
|
SERA Hedge Fund Activity: Q4 2025 in Review
57 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Sera Prognostics (SERA) for Q4 2025, worth a combined $52.4M — down 5.8% from $55.6M a quarter earlier.
Sellers outnumbered buyers: 8 funds closed out of SERA and 6 opened new positions — a net loss of 2 holders — while 14 trimmed existing stakes and 15 added.
The largest buyer was Corient Private Wealth, adding an estimated $323K. The largest seller was Sanders Morris Harris, exiting entirely with an estimated $807K sold.
- 57 institutional investors held Sera Prognostics (SERA) as of Q4 2025, down from 62 in Q3 2025.
- Funds reported $52.4M of Sera Prognostics stock for Q4 2025, down 5.8% quarter-over-quarter.
- 6 funds opened new Sera Prognostics positions in Q4 2025 and 8 closed out, a net change of -2 holders.
- The largest Sera Prognostics buyer in Q4 2025 was Corient Private Wealth, an estimated $323K added.
- The largest Sera Prognostics seller in Q4 2025 was Sanders Morris Harris, an estimated $807K sold.
Based on aggregated 13F filings for Q4 2025.