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Sera Prognostics

57 hedge funds and large institutions have $52.4M invested in Sera Prognostics in 2025 Q4 according to their latest regulatory filings, with 6 funds opening new positions, 15 increasing their positions, 14 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

7% more repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 14

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

2.32% less ownership

Funds ownership: 49.47%47.15% (-2.3%)

6% less capital invested

Capital invested by funds: $55.6M → $52.4M (-$3.21M)

8% less funds holding

Funds holding: 6257 (-5)

25% less first-time investments, than exits

New positions opened: 6 | Existing positions closed: 8

Holders
57
Holders Change
-5
Holders Change %
-8.06%
% of All Funds
0.69%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
6
Increased
15
Reduced
14
Closed
8
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Barclays
26
Barclays
United Kingdom
$108K +$86.2K +26,726 +267%
Squarepoint
27
Squarepoint
New York
$107K -$183K -56,741 -61%
Qube Research & Technologies (QRT)
28
Qube Research & Technologies (QRT)
United Kingdom
$85.5K +$15.8K +4,899 +20%
Goldman Sachs
29
Goldman Sachs
New York
$84.4K -$84.6K -26,240 -48%
BHIA
30
Birch Hill Investment Advisors
Massachusetts
$80.5K
UBS Group
31
UBS Group
Switzerland
$74.3K +$2.17K +672 +3%
Cetera Investment Advisers
32
Cetera Investment Advisers
Illinois
$73.8K +$80.6K +25,000 New
Dimensional Fund Advisors
33
Dimensional Fund Advisors
Texas
$67.5K +$1.65K +510 +2%
Two Sigma Investments
34
Two Sigma Investments
New York
$64.8K -$31.5K -9,772 -31%
Lido Advisors
35
Lido Advisors
California
$50.3K -$17.9K -5,541 -25%
Fidelity Investments
36
Fidelity Investments
Massachusetts
$43.8K
WWMSC
37
Wagner Wealth Management (South Carolina)
South Carolina
$37.4K +$923 +286 +2%
RCA
38
Riverview Capital Advisers
Massachusetts
$37.4K -$206 -64 -0.5%
Focus Partners Wealth
39
Focus Partners Wealth
Massachusetts
$35.9K
Charles Schwab
40
Charles Schwab
California
$35.7K -$23 -7 -0.1%
Point72 Asset Management
41
Point72 Asset Management
Connecticut
$33.6K +$36.8K +11,403 New
AHL
42
Abel Hall LLC
Louisiana
$32.6K
Wealth Enhancement Advisory Services
43
Wealth Enhancement Advisory Services
Minnesota
$31.5K +$34.3K +10,639 New
Deutsche Bank
44
Deutsche Bank
Germany
$25.8K
GWM
45
Geneos Wealth Management
Colorado
$23K +$10.6K +3,300 +73%
Bank of America
46
Bank of America
North Carolina
$13.8K -$2.5K -774 -14%
Carson Wealth (CWM LLC)
47
Carson Wealth (CWM LLC)
Nebraska
$3K -$3 -1 -0.1%
TRCT
48
Tower Research Capital (TRC)
New York
$2.79K +$3.05K +945 New
Optiver Holding
49
Optiver Holding
Netherlands
$1.22K
TM
50
Torren Management
California
$1.15K +$1.25K +389 New

SERA Hedge Fund Activity: Q4 2025 in Review

57 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Sera Prognostics (SERA) for Q4 2025, worth a combined $52.4M — down 5.8% from $55.6M a quarter earlier.

Sellers outnumbered buyers: 8 funds closed out of SERA and 6 opened new positions — a net loss of 2 holders — while 14 trimmed existing stakes and 15 added.

The largest buyer was Corient Private Wealth, adding an estimated $323K. The largest seller was Sanders Morris Harris, exiting entirely with an estimated $807K sold.

  • 57 institutional investors held Sera Prognostics (SERA) as of Q4 2025, down from 62 in Q3 2025.
  • Funds reported $52.4M of Sera Prognostics stock for Q4 2025, down 5.8% quarter-over-quarter.
  • 6 funds opened new Sera Prognostics positions in Q4 2025 and 8 closed out, a net change of -2 holders.
  • The largest Sera Prognostics buyer in Q4 2025 was Corient Private Wealth, an estimated $323K added.
  • The largest Sera Prognostics seller in Q4 2025 was Sanders Morris Harris, an estimated $807K sold.

Based on aggregated 13F filings for Q4 2025.