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Cassava Sciences
SAVA

Overview Fund Activity

97 hedge funds and large institutions have $22.2M invested in Cassava Sciences in 2025 Q2 according to their latest regulatory filings, with 18 funds opening new positions, 24 increasing their positions, 33 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
97
Holders Change
-20
Holders Change %
-17.09%
% of All Funds
1.3%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
18
Increased
24
Reduced
33
Closed
37
Calls
$2.27M
Puts
$1.29M
Net Calls
+$986K
Net Calls Change
-$372K

Top Buyers

1
Millennium Management
Millennium Management
New York
+$856K
2
CSS
Cubist Systematic Strategies
Connecticut
+$561K
3
SPS
Susquehanna Portfolio Strategies
Pennsylvania
+$242K
4
Group One Trading
Group One Trading
Illinois
+$220K
5
Goldman Sachs
Goldman Sachs
New York
+$211K

Top Sellers

1
BlackRock
BlackRock
New York
-$3.49M
2
NL
Nuveen LLC
North Carolina
-$1.95M
3
State Street
State Street
Massachusetts
-$1.19M
4
Geode Capital Management
Geode Capital Management
Massachusetts
-$912K
5
UBS Group
UBS Group
Switzerland
-$644K
Name Holding Trade Value Shares
Change 		Shares
Change %
Vanguard Group
1
Vanguard Group
Pennsylvania
$3.93M -$493K -272,235 -11%
BlackRock
2
BlackRock
New York
$2.8M -$3.49M -1,929,073 -56%
Two Sigma Advisers
3
Two Sigma Advisers
New York
$1.78M +$136K +75,000 +8%
JPMorgan Chase & Co
4
JPMorgan Chase & Co
New York
$1.37M -$59.6K -32,955 -4%
Goldman Sachs
5
Goldman Sachs
New York
$1.11M +$211K +116,830 +24%
Two Sigma Investments
6
Two Sigma Investments
New York
$953K +$170K +93,934 +22%
Geode Capital Management
7
Geode Capital Management
Massachusetts
$947K -$912K -503,720 -49%
Millennium Management
8
Millennium Management
New York
$856K +$856K +472,782 New
Morgan Stanley
9
Morgan Stanley
New York
$815K +$134K +74,197 +20%
GC
10
GMT Capital
Georgia
$815K – – –
Susquehanna International Group
11
Susquehanna International Group
Pennsylvania
$808K -$191K -105,591 -19%
Jane Street
12
Jane Street
New York
$613K +$112K +61,765 +22%
CSS
13
Cubist Systematic Strategies
Connecticut
$561K +$561K +309,701 New
Charles Schwab
14
Charles Schwab
California
$480K -$174K -95,963 -27%
TCM
15
Tang Capital Management
California
$434K +$72.1K +39,820 +20%
State Street
16
State Street
Massachusetts
$393K -$1.19M -656,619 -75%
Group One Trading
17
Group One Trading
Illinois
$392K +$220K +121,429 +128%
UBS Group
18
UBS Group
Switzerland
$344K -$644K -355,730 -65%
SPS
19
Susquehanna Portfolio Strategies
Pennsylvania
$242K +$242K +133,443 New
Squarepoint
20
Squarepoint
New York
$193K +$74.8K +41,345 +63%
Northern Trust
21
Northern Trust
Illinois
$184K -$484K -267,415 -72%
HF
22
HRT Financial
New York
$171K +$171K +94,855 New
BNP Paribas Financial Markets
23
BNP Paribas Financial Markets
France
$165K +$1.2K +660 +0.7%
Royal Bank of Canada
24
Royal Bank of Canada
Ontario, Canada
$153K +$151K +83,754 +7,777%
Marshall Wace
25
Marshall Wace
United Kingdom
$130K +$130K +71,714 New
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