|
1
|
Flagship Pioneering
Cambridge,
Massachusetts
|
$102M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$64.3M
|
-$543K
|
-147,438
|
-0.9%
|
|
|
3
|
Canada Pension Plan Investment Board
Toronto Ontario,
Ontario, Canada
|
$41.5M
|
–
|
–
|
–
|
|
|
4
|
Baillie Gifford & Co
Edinburgh,
United Kingdom
|
$41.4M
|
-$200K
|
-54,358
|
-0.5%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$40M
|
+$2.32M
|
+629,499
|
+7%
|
|
|
6
|
|
$34.6M
|
+$1.75M
|
+475,259
|
+6%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$24.1M
|
+$4.79M
|
+1,300,194
|
+28%
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$14.7M
|
-$12.6M
|
-3,432,116
|
-49%
|
|
|
9
|
Crestline Management
Fort Worth,
Texas
|
$13.7M
|
–
|
–
|
–
|
|
|
10
|
Alphabet Inc
Mountain View,
California
|
$11.5M
|
–
|
–
|
–
|
|
|
11
|
Geode Capital Management
Boston,
Massachusetts
|
$9.2M
|
+$760K
|
+206,248
|
+10%
|
|
|
12
|
Millennium Management
New York
|
$8.96M
|
+$6.2M
|
+1,682,828
|
+328%
|
|
|
13
|
Baker Bros. Advisors
New York
|
$8.16M
|
–
|
–
|
–
|
|
|
14
|
PFM Health Sciences
San Francisco,
California
|
$7.68M
|
+$2.35M
|
+639,198
|
+51%
|
|
|
15
|
Suvretta Capital Management
New York
|
$6.55M
|
-$5M
|
-1,357,648
|
-46%
|
|
|
16
|
Capital World Investors
Los Angeles,
California
|
$6.25M
|
–
|
–
|
–
|
|
|
17
|
|
$4.86M
|
+$49K
|
+13,302
|
+1%
|
|
|
18
|
Massachusetts Financial Services
Boston,
Massachusetts
|
$4.3M
|
-$25.1K
|
-6,810
|
-0.6%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$3.62M
|
+$200K
|
+54,366
|
+7%
|
|
|
20
|
Omega Fund Management
Boston,
Massachusetts
|
$3.44M
|
–
|
–
|
–
|
|
|
21
|
|
$3.39M
|
+$794K
|
+215,650
|
+35%
|
|
|
22
|
Charles Schwab
San Francisco,
California
|
$3.06M
|
+$64.5K
|
+17,519
|
+2%
|
|
|
23
|
|
$2.99M
|
+$517K
|
+140,439
|
+24%
|
|
|
24
|
Nuveen
Charlotte,
North Carolina
|
$2.97M
|
-$160K
|
-43,405
|
-6%
|
|
|
25
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$2.8M
|
+$797K
|
+216,376
|
+46%
|
|
