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SAGE

Sage Therapeutics
SAGE

Delisted

SAGE was delisted on the 30th of July, 2025.

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197 hedge funds and large institutions have $411M invested in Sage Therapeutics in 2025 Q1 according to their latest regulatory filings, with 58 funds opening new positions, 51 increasing their positions, 53 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more funds holding in top 10

Funds holding in top 10: 1 → 2 (+1)

57% more first-time investments, than exits

New positions opened: 58 | Existing positions closed: 37

48% more capital invested

Capital invested by funds: $278M → $411M (+$133M)

12% more funds holding

Funds holding: 176 → 197 (+21)

0.42% more ownership

Funds ownership: 83.74% → 84.15% (+0.42%)

4% less repeat investments, than reductions

Existing positions increased: 51 | Existing positions reduced: 53

20% less call options, than puts

Call options by funds: $2.1M | Put options by funds: $2.63M

Holders
197
Holders Change
+21
Holders Change %
+11.93%
% of All Funds
2.64%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
58
Increased
51
Reduced
53
Closed
37
Calls
$2.1M
Puts
$2.63M
Net Calls
-$526K
Net Calls Change
-$2.17M

Top Buyers

Rank Fund Capital Flow
1
MAP
Madison Avenue Partners
New York
+$32.8M
2
TAL
TIG Advisors LLC
New York
+$20M
3
DTC
Deep Track Capital
Connecticut
+$14.9M
4
Marshall Wace
Marshall Wace
United Kingdom
+$12.9M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$10M

Top Sellers

Rank Fund Capital Flow
1
Fidelity Investments
Fidelity Investments
Massachusetts
-$30.1M
2
BG
Bellevue Group
Switzerland
-$24.2M
3
Morgan Stanley
Morgan Stanley
New York
-$23.4M
4
RI
RTW Investments
New York
-$16.3M
5
Millennium Management
Millennium Management
New York
-$9.62M
Name Holding Trade Value Shares
Change 		Change in
Stake
Northern Trust
26
Northern Trust
Illinois
$3.72M -$413K -56,363 -11%
Charles Schwab
27
Charles Schwab
California
$3.55M -$118K -16,131 -3%
MAM
28
Monaco Asset Management
Monaco
$3.51M +$3.23M +441,619 New
Goldman Sachs
29
Goldman Sachs
New York
$3.48M -$763K -104,194 -19%
RC
30
Rangeley Capital
Connecticut
$3.06M +$2.82M +384,687 New
Two Sigma Investments
31
Two Sigma Investments
New York
$2.85M +$1.67M +228,635 +176%
Two Sigma Advisers
32
Two Sigma Advisers
New York
$2.58M +$1.52M +207,200 +176%
Millennium Management
33
Millennium Management
New York
$2.46M -$9.62M -1,314,245 -81%
Deutsche Bank
34
Deutsche Bank
Germany
$1.78M +$1.27M +173,164 +341%
PA
35
Pinnacle Associates
New York
$1.74M -$13.6K -1,854 -0.8%
SFI
36
Susquehanna Fundamental Investments
Pennsylvania
$1.68M -$31.5K -4,308 -2%
Bank of America
37
Bank of America
North Carolina
$1.62M -$825K -112,676 -36%
GL
38
Governors Lane
New York
$1.61M +$1.48M +202,400 New
Susquehanna International Group
39
Susquehanna International Group
Pennsylvania
$1.59M +$924K +126,137 +171%
Jane Street
40
Jane Street
New York
$1.54M -$1.97M -268,823 -58%
JF
41
Jump Financial
Illinois
$1.5M +$1.38M +188,598 New
Connor, Clark & Lunn Investment Management (CC&L)
42
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$1.49M +$132K +17,991 +11%
DP
43
Diadema Partners
New Jersey
$1.46M +$1.34M +183,466 New
AGM
44
Alpine Global Management
New York
$1.43M +$1.32M +180,000 New
Bank of New York Mellon
45
Bank of New York Mellon
New York
$1.37M +$9.42K +1,287 +0.8%
Verition Fund Management
46
Verition Fund Management
Connecticut
$1.37M +$22K +3,008 +2%
ECM
47
Eisler Capital Management
United Kingdom
$1.35M +$1.24M +170,000 New
IC
48
IEQ Capital
California
$1.31M +$1.13M +154,183 +1,473%
Invesco
49
Invesco
Georgia
$1.29M +$512K +69,966 +76%
HF
50
HRT Financial
New York
$1.2M -$3.72K -508 -0.3%
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SAGE Hedge Fund Activity: Q1 2025 in Review

197 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Sage Therapeutics (SAGE) for Q1 2025, worth a combined $411M — up 48% from $278M a quarter earlier.

Buyers outnumbered sellers: 58 funds opened new SAGE positions and 37 closed out — a net gain of 21 holders — while 51 added to existing stakes and 53 trimmed.

The largest buyer was Madison Avenue Partners, opening a new position worth an estimated $32.8M. The largest seller was Fidelity Investments, cutting an estimated $30.1M.

  • 197 institutional investors held Sage Therapeutics (SAGE) as of Q1 2025, up from 176 in Q4 2024.
  • Funds reported $411M of Sage Therapeutics stock for Q1 2025, up 48% quarter-over-quarter.
  • 58 funds opened new Sage Therapeutics positions in Q1 2025 and 37 closed out, a net change of +21 holders.
  • The largest Sage Therapeutics buyer in Q1 2025 was Madison Avenue Partners, an estimated $32.8M added.
  • The largest Sage Therapeutics seller in Q1 2025 was Fidelity Investments, an estimated $30.1M sold.

Based on aggregated 13F filings for Q1 2025.