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Revolution Medicines

386 hedge funds and large institutions have $15.9B invested in Revolution Medicines in 2025 Q4 according to their latest regulatory filings, with 107 funds opening new positions, 135 increasing their positions, 101 reducing their positions, and 39 closing their positions.

New
Increased
Maintained
Reduced
Closed

546% more call options, than puts

Call options by funds: $247M | Put options by funds: $38.2M

174% more first-time investments, than exits

New positions opened: 107 | Existing positions closed: 39

77% more capital invested

Capital invested by funds: $8.96B → $15.9B (+$6.92B)

38% more funds holding in top 10

Funds holding in top 10: 2433 (+9)

34% more repeat investments, than reductions

Existing positions increased: 135 | Existing positions reduced: 101

20% more funds holding

Funds holding: 323386 (+63)

0.46% more ownership

Funds ownership: 102.63%103.09% (+0.46%)

Holders
386
Holders Change
+63
Holders Change %
+19.5%
% of All Funds
4.7%
Holding in Top 10
33
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+37.5%
% of All Funds
0.4%
New
107
Increased
135
Reduced
101
Closed
39
Calls
$247M
Puts
$38.2M
Net Calls
+$208M
Net Calls Change
+$127M
Name Holding Trade Value Shares
Change
Change in
Stake
FLSM
51
Frazier Life Sciences Management
California
$63.5M -$13.1M -200,000 -20%
Morgan Stanley
52
Morgan Stanley
New York
$51.9M -$51.3M -782,910 -55%
FTM
53
First Turn Management
California
$50.8M -$306K -4,665 -0.7%
BNP Paribas Financial Markets
54
BNP Paribas Financial Markets
France
$49.3M +$12.8M +194,706 +46%
DCM
55
DAFNA Capital Management
California
$48.1M -$3.45M -52,662 -8%
Bank of New York Mellon
56
Bank of New York Mellon
New York
$43.2M +$839K +12,799 +2%
MCMU
57
MIC Capital Management (UK)
United Kingdom
$40.5M
MB
58
MPM BioImpact
Massachusetts
$40.3M +$12.5M +189,950 +60%
Royal Bank of Canada
59
Royal Bank of Canada
Ontario, Canada
$40.1M +$20.4M +311,392 +162%
American Century Companies
60
American Century Companies
Missouri
$37.2M +$1.07M +16,346 +4%
Point72 Asset Management
61
Point72 Asset Management
Connecticut
$35.6M +$29.3M +446,616 New
TCM
62
TCG Crossover Management
California
$34.8M
FCM
63
Frontier Capital Management
Massachusetts
$34.3M +$20.2M +307,988 +251%
Two Sigma Investments
64
Two Sigma Investments
New York
$33.6M +$27.1M +412,628 +4,531%
JP Morgan Chase
65
JP Morgan Chase
New York
$33.6M -$136M -2,076,700 -83%
Balyasny Asset Management
66
Balyasny Asset Management
Illinois
$33.1M +$21M +319,611 +334%
N
67
Nuveen
North Carolina
$32.4M +$4.51M +68,767 +20%
BCM
68
Boxer Capital Management
California
$31.9M
Lord, Abbett & Co
69
Lord, Abbett & Co
New Jersey
$31.8M +$26.2M +399,484 New
Marshall Wace
70
Marshall Wace
United Kingdom
$30.8M +$14.8M +225,095 +140%
EAM
71
Eventide Asset Management
Massachusetts
$30.1M -$14.2M -216,777 -36%
TD Asset Management
72
TD Asset Management
Ontario, Canada
$29.5M -$10.8M -165,084 -31%
CC
73
Checkpoint Capital
California
$29.5M -$8.02M -122,300 -25%
Invesco
74
Invesco
Georgia
$29.3M +$10.9M +166,909 +83%
DCM
75
Defilade Capital Management
California
$28.9M +$23.8M +363,454 New