Two Sigma Investments
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Two Sigma Investments’s Revolution Medicines RVMD Stock Holding History

Two Sigma Investments’s Portfolio RVMD Stock Details RVMD Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$152M Buy
1,558,807
+1,137,072
+270% +$115M 0.12% 191
2025
Q4 		$33.6M Buy
421,735
+412,628
+4,531% +$27.1M 0.05% 492
2025
Q3 		$425K Buy
+9,107
New +$357K ﹤0.01% 3062
2024
Q4 		– Sell
-22,895
Closed -$1.04M – 3439
2024
Q3 		$1.04M Buy
22,895
+138
+0.6% +$6.01K ﹤0.01% 2098
2024
Q2 		$883K Sell
22,757
-2,400
-10% -$89.7K ﹤0.01% 2058
2024
Q1 		$811K Sell
25,157
-64,800
-72% -$1.92M ﹤0.01% 2082
2023
Q4 		$2.58M Buy
89,957
+15,643
+21% +$376K 0.01% 1349
2023
Q3 		$2.06M Buy
74,314
+14
+0% +$415 0.01% 1371
2023
Q2 		$1.99M Sell
74,300
-29,460
-28% -$723K 0.01% 1441
2023
Q1 		$2.25M Buy
103,760
+76,560
+281% +$1.89M 0.01% 1311
2022
Q4 		$648K Sell
27,200
-111,254
-80% -$2.37M ﹤0.01% 1912
2022
Q3 		$2.73M Buy
138,454
+83,950
+154% +$1.84M 0.01% 1006
2022
Q2 		$1.06M Sell
54,504
-86,377
-61% -$1.68M ﹤0.01% 1518
2022
Q1 		$3.59M Buy
140,881
+13,436
+11% +$292K 0.01% 1084
2021
Q4 		$3.21M Buy
127,445
+14,011
+12% +$395K 0.01% 1528
2021
Q3 		$3.12M Sell
113,434
-8,372
-7% -$244K 0.01% 1580
2021
Q2 		$3.87M Buy
121,806
+101,274
+493% +$3.53M 0.01% 1353
2021
Q1 		$942K Buy
+20,532
New +$921K ﹤0.01% 2380

Other funds holding RVMD

FCM
Farallon Capital Management San Francisco, California $17.5B AUM 50.95% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
BBA
Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
NI
Nextech Invest Zurich, Switzerland $1.42B AUM 304.47% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
PBA
Paradigm Biocapital Advisors New York $4.89B AUM 251.12% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return

Two Sigma Investments's RVMD Position: Q1 2026 in Review

Two Sigma Investments increased its Revolution Medicines (RVMD) stake by 270% in Q1 2026, buying an estimated $115M and bringing the position to 1,558,807 shares worth $152M. The position accounts for 0.12% of the portfolio, ranked #191.

Two Sigma Investments first reported a position in RVMD in Q1 2021 and has held it in 18 quarters since. 512 funds tracked by Wall St. Rank hold RVMD as of Q1 2026.

  • Two Sigma Investments held 1,558,807 shares of Revolution Medicines worth $152M as of Q1 2026.
  • Two Sigma Investments bought 1,137,072 Revolution Medicines shares in Q1 2026, an estimated $115M.
  • Revolution Medicines made up 0.12% of Two Sigma Investments's portfolio in Q1 2026, its #191 holding.
  • Two Sigma Investments first reported a position in Revolution Medicines in Q1 2021 and has held it in 18 quarters since.
  • 512 funds tracked by Wall St. Rank held Revolution Medicines as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.