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Royalty Pharma

448 hedge funds and large institutions have $10.1B invested in Royalty Pharma in 2025 Q1 according to their latest regulatory filings, with 84 funds opening new positions, 160 increasing their positions, 150 reducing their positions, and 51 closing their positions.

New
Increased
Maintained
Reduced
Closed

160% more call options, than puts

Call options by funds: $89M | Put options by funds: $34.2M

65% more first-time investments, than exits

New positions opened: 84 | Existing positions closed: 51

7% more funds holding

Funds holding: 418 → 448 (+30)

2.07% more ownership

Funds ownership: 72.43% → 74.49% (+2.1%)

7% more repeat investments, than reductions

Existing positions increased: 160 | Existing positions reduced: 150

6% more capital inflows, than outflows

Capital inflows: $1.25B | Capital outflows: $1.18B

22% less funds holding in top 10

Funds holding in top 10: 9 → 7 (-2)

Holders
448
Holders Change
+30
Holders Change %
+7.18%
% of All Funds
5.99%
Holding in Top 10
7
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-22.22%
% of All Funds
0.09%
New
84
Increased
160
Reduced
150
Closed
51
Calls
$89M
Puts
$34.2M
Net Calls
+$54.8M
Net Calls Change
+$39.9M

RPRX Hedge Fund Activity: Q1 2025 in Review

448 of the 7,478 institutional investors tracked by Wall St. Rank reported a position in Royalty Pharma (RPRX) for Q1 2025, worth a combined $10.1B — up 22% from $8.21B a quarter earlier.

Buyers outnumbered sellers: 84 funds opened new RPRX positions and 51 closed out — a net gain of 33 holders — while 160 added to existing stakes and 150 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $413M. The largest seller was Adage Capital Partners, cutting an estimated $340M.

  • 448 institutional investors held Royalty Pharma (RPRX) as of Q1 2025, up from 418 in Q4 2024.
  • Funds reported $10.1B of Royalty Pharma stock for Q1 2025, up 22% quarter-over-quarter.
  • 84 funds opened new Royalty Pharma positions in Q1 2025 and 51 closed out, a net change of +33 holders.
  • The largest Royalty Pharma buyer in Q1 2025 was Fidelity Investments, an estimated $413M added.
  • The largest Royalty Pharma seller in Q1 2025 was Adage Capital Partners, an estimated $340M sold.

Based on aggregated 13F filings for Q1 2025.