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Royalty Pharma
RPRX

447 hedge funds and large institutions have $10.1B invested in Royalty Pharma in 2025 Q1 according to their latest regulatory filings, with 84 funds opening new positions, 160 increasing their positions, 149 reducing their positions, and 50 closing their positions.

New
Increased
Maintained
Reduced
Closed

160% more call options, than puts

Call options by funds: $89M | Put options by funds: $34.2M

68% more first-time investments, than exits

New positions opened: 84 | Existing positions closed: 50

22% more capital invested

Capital invested by funds: $8.21B → $10.1B (+$1.84B)

7% more funds holding

Funds holding: 416 → 447 (+31)

2.07% more ownership

Funds ownership: 72.43% → 74.49% (+2.1%)

7% more repeat investments, than reductions

Existing positions increased: 160 | Existing positions reduced: 149

22% less funds holding in top 10

Funds holding in top 10: 9 → 7 (-2)

Holders
447
Holders Change
+31
Holders Change %
+7.45%
% of All Funds
5.99%
Holding in Top 10
7
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-22.22%
% of All Funds
0.09%
New
84
Increased
160
Reduced
149
Closed
50
Calls
$89M
Puts
$34.2M
Net Calls
+$54.8M
Net Calls Change
+$39.9M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$413M
2
CIA
Caledonia Investments (Australia)
Australia
+$162M
3
Victory Capital Management
Victory Capital Management
Texas
+$83.8M
4
Morgan Stanley
Morgan Stanley
New York
+$47.5M
5
Los Angeles Capital Management
Los Angeles Capital Management
California
+$33M

Top Sellers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$340M
2
Millennium Management
Millennium Management
New York
-$66.8M
3
SGA
Siguler Guff Advisers
New York
-$60.4M
4
Deutsche Bank
Deutsche Bank
Germany
-$56.3M
5
Viking Global Investors
Viking Global Investors
Connecticut
-$52.1M
Name Holding Trade Value Shares
Change 		Change in
Stake
SRL
326
Scientech Research LLC
New Jersey
$254K -$65.5K -2,068 -20%
MFG
327
Merit Financial Group
Georgia
$252K +$257K +8,097 New
VI
328
Vestcor Inc
New Brunswick, Canada
$252K – – –
AAMU
329
APG Asset Management US
New York
$245K – – –
AFG
330
Atomi Financial Group
New York
$244K +$248K +7,838 New
EWA
331
EP Wealth Advisors
California
$242K +$247K +7,785 New
BP
332
Ballentine Partners
Massachusetts
$242K -$2.28K -72 -0.9%
CI Investments Inc
333
CI Investments Inc
Ontario, Canada
$240K -$124K -3,918 -34%
SPIA
334
Steward Partners Investment Advisory
New York
$239K +$102K +3,231 +73%
YIH
335
Y-Intercept (HK)
Hong Kong
$238K +$242K +7,649 New
Northwestern Mutual Wealth Management
336
Northwestern Mutual Wealth Management
Wisconsin
$237K +$36.5K +1,151 +18%
Vontobel Holding
337
Vontobel Holding
Switzerland
$234K -$47.4K -1,494 -17%
C
338
Covestor
United Kingdom
$232K -$17.2K -542 -7%
1C
339
111 Capital
France
$228K -$831K -26,204 -78%
PTC
340
Petrus Trust Company
Texas
$227K +$231K +7,287 New
SFS
341
Sowell Financial Services
Arkansas
$220K +$224K +7,075 New
AGP
342
Autumn Glory Partners
Texas
$218K +$222K +7,000 New
Mercer Global Advisors
343
Mercer Global Advisors
Colorado
$217K +$236K +7,453 New
MIM
344
MetLife Investment Management
New Jersey
$216K +$1.81K +57 +0.8%
CIAM
345
Caitong International Asset Management
Hong Kong
$213K +$216K +6,829 New
William Blair & Company
346
William Blair & Company
Illinois
$212K +$216K +6,801 New
SCM
347
Semanteon Capital Management
Massachusetts
$212K +$216K +6,800 New
PP
348
PDS Planning
Ohio
$206K +$209K +6,603 New
FRA
349
Frank Rimerman Advisors
California
$205K +$209K +6,592 New
GSWA
350
Good Steward Wealth Advisors
Tennessee
$205K +$209K +6,585 New
12 13
14
15 16

RPRX Hedge Fund Activity: Q1 2025 in Review

447 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Royalty Pharma (RPRX) for Q1 2025, worth a combined $10.1B — up 22% from $8.21B a quarter earlier.

Buyers outnumbered sellers: 84 funds opened new RPRX positions and 50 closed out — a net gain of 34 holders — while 160 added to existing stakes and 149 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $413M. The largest seller was Adage Capital Partners, cutting an estimated $340M.

  • 447 institutional investors held Royalty Pharma (RPRX) as of Q1 2025, up from 416 in Q4 2024.
  • Funds reported $10.1B of Royalty Pharma stock for Q1 2025, up 22% quarter-over-quarter.
  • 84 funds opened new Royalty Pharma positions in Q1 2025 and 50 closed out, a net change of +34 holders.
  • The largest Royalty Pharma buyer in Q1 2025 was Fidelity Investments, an estimated $413M added.
  • The largest Royalty Pharma seller in Q1 2025 was Adage Capital Partners, an estimated $340M sold.

Based on aggregated 13F filings for Q1 2025.