|
1
|
Vivo Capital
Palo Alto,
California
|
$18.9M
|
+$25.3M
|
+261,550
|
New
|
|
|
2
|
Mangrove Partners
Greenwich,
Connecticut
|
$13.4M
|
+$947K
|
+9,811
|
+6%
|
|
|
3
|
EcoR1 Capital
San Francisco,
California
|
$11.1M
|
–
|
–
|
–
|
|
|
4
|
BVF Inc
San Francisco,
California
|
$8.7M
|
+$1.05M
|
+10,847
|
+10%
|
|
|
5
|
|
$8.23M
|
–
|
–
|
–
|
|
|
6
|
Boxer Capital
San Diego,
California
|
$7.92M
|
–
|
–
|
–
|
|
|
7
|
Wasatch Advisors
Salt Lake City,
Utah
|
$7.77M
|
-$3.84M
|
-39,775
|
-27%
|
|
|
8
|
Polaris Venture Management Co V
Boston,
Massachusetts
|
$6.68M
|
–
|
–
|
–
|
|
|
9
|
|
$6.25M
|
-$918K
|
-9,507
|
-10%
|
|
|
10
|
Millennium Management
New York
|
$6.21M
|
+$3.8M
|
+39,392
|
+85%
|
|
|
11
|
Acuta Capital Partners
Redwood City,
California
|
$5.7M
|
–
|
–
|
–
|
|
|
12
|
Ghost Tree Capital
New York
|
$4.16M
|
+$1.85M
|
+19,167
|
+50%
|
|
|
13
|
Citadel Advisors
Miami,
Florida
|
$4.09M
|
+$5.46M
|
+56,511
|
New
|
|
|
14
|
Vanguard Group
Malvern,
Pennsylvania
|
$3.9M
|
+$869K
|
+8,999
|
+20%
|
|
|
15
|
Renaissance Technologies
New York
|
$3.55M
|
+$1.93M
|
+20,021
|
+69%
|
|
|
16
|
Logos Global Management
San Francisco,
California
|
$2.68M
|
+$3.58M
|
+37,062
|
New
|
|
|
17
|
RA Capital Management
Boston,
Massachusetts
|
$2.1M
|
+$2.8M
|
+29,021
|
New
|
|
|
18
|
Point72 Asset Management
Stamford,
Connecticut
|
$2.08M
|
+$2.78M
|
+28,784
|
New
|
|
|
19
|
683 Capital Management
New York
|
$1.72M
|
+$2.3M
|
+23,821
|
New
|
|
|
20
|
|
$1.68M
|
+$117K
|
+1,211
|
+6%
|
|
|
21
|
Pura Vida Investments
New York
|
$1.51M
|
+$2.01M
|
+20,825
|
New
|
|
|
22
|
Opaleye Management
Boston,
Massachusetts
|
$940K
|
+$1.26M
|
+13,000
|
New
|
|
|
23
|
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
$696K
|
+$929K
|
+9,621
|
New
|
|
|
24
|
Geode Capital Management
Boston,
Massachusetts
|
$688K
|
+$15.4K
|
+160
|
+2%
|
|
|
25
|
Endurant Capital Management
San Mateo,
California
|
$615K
|
+$739K
|
+7,650
|
+890%
|
|
