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Rallybio
RLYB

47 hedge funds and large institutions have $20.9M invested in Rallybio in 2025 Q1 according to their latest regulatory filings, with 2 funds opening new positions, 9 increasing their positions, 15 reducing their positions, and 4 closing their positions.

New
Increased
Maintained
Reduced
Closed

0% more funds holding in top 10

Funds holding in top 10: 4 → 4 (0)

0.16% less ownership

Funds ownership: 9.77% → 9.61% (-0.16%)

4% less funds holding

Funds holding: 49 → 47 (-2)

33% less capital invested

Capital invested by funds: $31.1M → $20.9M (-$10.2M)

40% less repeat investments, than reductions

Existing positions increased: 9 | Existing positions reduced: 15

50% less first-time investments, than exits

New positions opened: 2 | Existing positions closed: 4

Holders
47
Holders Change
-2
Holders Change %
-4.08%
% of All Funds
0.63%
Holding in Top 10
4
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.05%
New
2
Increased
9
Reduced
15
Closed
4
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
Citadel Advisors
Citadel Advisors
Florida
+$41.7K
2
Vanguard Group
Vanguard Group
Pennsylvania
+$36.7K
3
Fidelity Investments
Fidelity Investments
Massachusetts
+$14.6K
4
Squarepoint
Squarepoint
New York
+$12.7K
5
Jane Street
Jane Street
New York
+$8.39K

Top Sellers

Rank Fund Capital Flow
1
CPX
Canaan Partners XI
California
-$130K
2
NFC
Northeast Financial Consultants
Connecticut
-$92.6K
3
Millennium Management
Millennium Management
New York
-$88.2K
4
AI
Allostery Investments
Connecticut
-$40.4K
5
Renaissance Technologies
Renaissance Technologies
New York
-$35.4K
Name Holding Trade Value Shares
Change 		Change in
Stake
Viking Global Investors
1
Viking Global Investors
Connecticut
$2.75M – – –
JJ
2
Johnson & Johnson
New Jersey
$2.38M – – –
5VM
3
5AM Venture Management
California
$2.38M – – –
NLVP
4
New Leaf Venture Partners
New York
$2.15M – – –
TGA
5
TPG GP A
Texas
$1.98M – – –
PBPIA
6
Pivotal bioVenture Partners Investment Advisor
California
$1.56M – – –
Fidelity Investments
7
Fidelity Investments
Massachusetts
$1.17M +$14.6K +2,314 +1%
Aberdeen Group
8
Aberdeen Group
United Kingdom
$1.13M – – –
CPX
9
Canaan Partners XI
California
$1M -$130K -20,642 -10%
AC
10
Almitas Capital
California
$851K +$1.95K +308 +0.2%
Vanguard Group
11
Vanguard Group
Pennsylvania
$637K +$36.7K +5,801 +5%
AIIC
12
AJU IB Investment Company
South Korea
$494K – – –
AI
13
Allostery Investments
Connecticut
$492K -$40.4K -6,396 -6%
LCM
14
Laurion Capital Management
New York
$481K – – –
Mariner
15
Mariner
Kansas
$265K – – –
Renaissance Technologies
16
Renaissance Technologies
New York
$260K -$35.4K -5,602 -10%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$162K -$215 -34 -0.1%
Millennium Management
18
Millennium Management
New York
$149K -$88.2K -13,960 -33%
BlackRock
19
BlackRock
New York
$137K +$6.48K +1,025 +4%
BCM
20
Bridgeway Capital Management
Texas
$60K – – –
Two Sigma Advisers
21
Two Sigma Advisers
New York
$59.6K -$221 -35 -0.3%
Acadian Asset Management
22
Acadian Asset Management
Massachusetts
$57K – – –
Two Sigma Investments
23
Two Sigma Investments
New York
$43.7K -$7.97K -1,262 -13%
State Street
24
State Street
Massachusetts
$40.6K – – –
Citadel Advisors
25
Citadel Advisors
Florida
$34.6K +$41.7K +6,601 New
1
2 3

RLYB Hedge Fund Activity: Q1 2025 in Review

47 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Rallybio (RLYB) for Q1 2025, worth a combined $20.9M — down 33% from $31.1M a quarter earlier.

Sellers outnumbered buyers: 4 funds closed out of RLYB and 2 opened new positions — a net loss of 2 holders — while 15 trimmed existing stakes and 9 added.

The largest buyer was Citadel Advisors, opening a new position worth an estimated $41.7K. The largest seller was Canaan Partners XI, cutting an estimated $130K.

  • 47 institutional investors held Rallybio (RLYB) as of Q1 2025, down from 49 in Q4 2024.
  • Funds reported $20.9M of Rallybio stock for Q1 2025, down 33% quarter-over-quarter.
  • 2 funds opened new Rallybio positions in Q1 2025 and 4 closed out, a net change of -2 holders.
  • The largest Rallybio buyer in Q1 2025 was Citadel Advisors, an estimated $41.7K added.
  • The largest Rallybio seller in Q1 2025 was Canaan Partners XI, an estimated $130K sold.

Based on aggregated 13F filings for Q1 2025.