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Rigel Pharmaceuticals

193 hedge funds and large institutions have $691M invested in Rigel Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 51 funds opening new positions, 67 increasing their positions, 62 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

320% more call options, than puts

Call options by funds: $7.71M | Put options by funds: $1.84M

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

96% more first-time investments, than exits

New positions opened: 51 | Existing positions closed: 26

62% more capital invested

Capital invested by funds: $426M → $691M (+$265M)

14% more funds holding

Funds holding: 169193 (+24)

5.17% more ownership

Funds ownership: 83.75%88.92% (+5.2%)

8% more repeat investments, than reductions

Existing positions increased: 67 | Existing positions reduced: 62

Holders
193
Holders Change
+24
Holders Change %
+14.2%
% of All Funds
2.35%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.02%
New
51
Increased
67
Reduced
62
Closed
26
Calls
$7.71M
Puts
$1.84M
Net Calls
+$5.87M
Net Calls Change
+$5.32M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$71.3M -$2.29M -60,688 -4%
State Street
2
State Street
Massachusetts
$46.7M +$20.2M +536,905 +97%
Vanguard Group
3
Vanguard Group
Pennsylvania
$44.5M -$178K -4,715 -0.5%
AC
4
Armistice Capital
New York
$35.8M +$4.22M +112,000 +15%
Goldman Sachs
5
Goldman Sachs
New York
$28.8M -$2.46M -65,157 -9%
Marshall Wace
6
Marshall Wace
United Kingdom
$26.3M +$462K +12,267 +2%
LSV Asset Management
7
LSV Asset Management
Illinois
$23.3M +$16.3M +433,382 +391%
Renaissance Technologies
8
Renaissance Technologies
New York
$23.1M +$2.44M +64,800 +14%
Acadian Asset Management
9
Acadian Asset Management
Massachusetts
$21.1M -$7.24M -192,114 -28%
Millennium Management
10
Millennium Management
New York
$18.5M +$12.3M +326,159 +310%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$18.2M +$22.3K +591 +0.1%
D.E. Shaw & Co
12
D.E. Shaw & Co
New York
$18.2M +$4.44M +117,827 +38%
Arrowstreet Capital
13
Arrowstreet Capital
Massachusetts
$17.7M +$8.57M +227,333 +122%
SCM
14
Soleus Capital Management
Connecticut
$12.9M -$1.13M -29,976 -9%
Qube Research & Technologies (QRT)
15
Qube Research & Technologies (QRT)
United Kingdom
$12.3M -$2.74M -72,697 -20%
HIM
16
Hillsdale Investment Management
Ontario, Canada
$12.1M -$68.2K -1,810 -0.6%
Dimensional Fund Advisors
17
Dimensional Fund Advisors
Texas
$11.9M +$2.54M +67,425 +32%
Jane Street
18
Jane Street
New York
$11.8M -$1.73M -46,011 -14%
Two Sigma Investments
19
Two Sigma Investments
New York
$11.6M +$1.92M +50,930 +23%
N
20
Nuveen
North Carolina
$11.1M +$4.73M +125,426 +94%
American Century Companies
21
American Century Companies
Missouri
$10.9M +$9.59M +254,492 New
CM
22
CM Management
Florida
$9.64M
GC
23
Globeflex Capital
California
$9.33M +$7.88K +209 +0.1%
TI
24
Trexquant Investment
Connecticut
$8.44M +$1.13M +30,030 +18%
Citadel Advisors
25
Citadel Advisors
Florida
$7.94M +$3.73M +98,955 +114%

RIGL Hedge Fund Activity: Q4 2025 in Review

193 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Rigel Pharmaceuticals (RIGL) for Q4 2025, worth a combined $691M — up 62% from $426M a quarter earlier.

Buyers outnumbered sellers: 51 funds opened new RIGL positions and 26 closed out — a net gain of 25 holders — while 67 added to existing stakes and 62 trimmed.

The largest buyer was State Street, adding an estimated $20.2M. The largest seller was Capitolis Liquid Global Markets, exiting entirely with an estimated $16.8M sold.

  • 193 institutional investors held Rigel Pharmaceuticals (RIGL) as of Q4 2025, up from 169 in Q3 2025.
  • Funds reported $691M of Rigel Pharmaceuticals stock for Q4 2025, up 62% quarter-over-quarter.
  • 51 funds opened new Rigel Pharmaceuticals positions in Q4 2025 and 26 closed out, a net change of +25 holders.
  • The largest Rigel Pharmaceuticals buyer in Q4 2025 was State Street, an estimated $20.2M added.
  • The largest Rigel Pharmaceuticals seller in Q4 2025 was Capitolis Liquid Global Markets, an estimated $16.8M sold.

Based on aggregated 13F filings for Q4 2025.