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Rigel Pharmaceuticals

193 hedge funds and large institutions have $691M invested in Rigel Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 51 funds opening new positions, 67 increasing their positions, 62 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

320% more call options, than puts

Call options by funds: $7.71M | Put options by funds: $1.84M

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

96% more first-time investments, than exits

New positions opened: 51 | Existing positions closed: 26

62% more capital invested

Capital invested by funds: $426M → $691M (+$265M)

14% more funds holding

Funds holding: 169193 (+24)

5.17% more ownership

Funds ownership: 83.75%88.92% (+5.2%)

8% more repeat investments, than reductions

Existing positions increased: 67 | Existing positions reduced: 62

Holders
193
Holders Change
+24
Holders Change %
+14.2%
% of All Funds
2.35%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.02%
New
51
Increased
67
Reduced
62
Closed
26
Calls
$7.71M
Puts
$1.84M
Net Calls
+$5.87M
Net Calls Change
+$5.32M
Name Holding Trade Value Shares
Change
Change in
Stake
Morgan Stanley
26
Morgan Stanley
New York
$7.13M +$762K +20,223 +14%
Charles Schwab
27
Charles Schwab
California
$6.37M -$1.18M -31,172 -17%
Prudential Financial
28
Prudential Financial
New Jersey
$5.8M -$1.13M -29,919 -18%
Northern Trust
29
Northern Trust
Illinois
$5.53M -$327K -8,676 -6%
ZIM
30
Zacks Investment Management
Illinois
$5.1M -$345K -9,143 -7%
Bank of America
31
Bank of America
North Carolina
$5.01M +$1.56M +41,476 +55%
AQR Capital Management
32
AQR Capital Management
Connecticut
$4.7M +$2M +53,135 +94%
Bank of New York Mellon
33
Bank of New York Mellon
New York
$4.64M +$392K +10,405 +11%
OSAM
34
O'Shaughnessy Asset Management
Connecticut
$4.63M +$3.6M +95,605 +772%
Connor, Clark & Lunn Investment Management (CC&L)
35
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$4.62M -$4.54M -120,426 -53%
RWM
36
Ritholtz Wealth Management
New York
$3.45M +$2.75M +72,999 +961%
EFMC
37
Empire Financial Management Company
New York
$3.27M -$493K -13,066 -15%
Barclays
38
Barclays
United Kingdom
$3.23M +$916K +24,294 +48%
Russell Investments Group
39
Russell Investments Group
United Kingdom
$3.16M -$1.66M -44,135 -37%
BGIM
40
Brandywine Global Investment Management
Pennsylvania
$3.07M -$98K -2,600 -4%
OM
41
Opaleye Management
Massachusetts
$3M +$1.21M +32,213 +85%
Fidelity Investments
42
Fidelity Investments
Massachusetts
$2.91M +$330K +8,751 +15%
Pacer Advisors
43
Pacer Advisors
Pennsylvania
$2.81M -$451K -11,976 -15%
First Trust Advisors
44
First Trust Advisors
Illinois
$2.78M +$272K +7,204 +13%
Wells Fargo
45
Wells Fargo
California
$2.66M +$44.1K +1,171 +2%
Schroder Investment Management Group
46
Schroder Investment Management Group
United Kingdom
$2.61M -$406K -10,777 -15%
Wellington Management Group
47
Wellington Management Group
Massachusetts
$2.44M -$180K -4,769 -8%
Man Group
48
Man Group
United Kingdom
$2.43M +$1.28M +33,853 +148%
Universal-Beteiligungs- und Servicegesellschaft
49
Universal-Beteiligungs- und Servicegesellschaft
Germany
$2.36M +$2.08M +55,200 New
Squarepoint
50
Squarepoint
New York
$2.29M -$4.49M -119,082 -69%

RIGL Hedge Fund Activity: Q4 2025 in Review

193 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Rigel Pharmaceuticals (RIGL) for Q4 2025, worth a combined $691M — up 62% from $426M a quarter earlier.

Buyers outnumbered sellers: 51 funds opened new RIGL positions and 26 closed out — a net gain of 25 holders — while 67 added to existing stakes and 62 trimmed.

The largest buyer was State Street, adding an estimated $20.2M. The largest seller was Capitolis Liquid Global Markets, exiting entirely with an estimated $16.8M sold.

  • 193 institutional investors held Rigel Pharmaceuticals (RIGL) as of Q4 2025, up from 169 in Q3 2025.
  • Funds reported $691M of Rigel Pharmaceuticals stock for Q4 2025, up 62% quarter-over-quarter.
  • 51 funds opened new Rigel Pharmaceuticals positions in Q4 2025 and 26 closed out, a net change of +25 holders.
  • The largest Rigel Pharmaceuticals buyer in Q4 2025 was State Street, an estimated $20.2M added.
  • The largest Rigel Pharmaceuticals seller in Q4 2025 was Capitolis Liquid Global Markets, an estimated $16.8M sold.

Based on aggregated 13F filings for Q4 2025.