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Repligen

Name Holding Trade Value Shares
Change
Change in
Stake
T. Rowe Price Associates
1
T. Rowe Price Associates
Maryland
$821M -$122M -962,139 -13%
BlackRock
2
BlackRock
New York
$756M -$93.8M -737,257 -11%
Vanguard Group
3
Vanguard Group
Pennsylvania
$631M -$346K -2,722 -0.1%
Point72 Asset Management
4
Point72 Asset Management
Connecticut
$238M +$101M +796,745 +71%
State Street
5
State Street
Massachusetts
$202M -$8.44M -66,314 -4%
Fidelity Investments
6
Fidelity Investments
Massachusetts
$201M +$112M +880,900 +120%
CIP
7
Champlain Investment Partners
Vermont
$174M -$8.01M -62,907 -4%
Invesco
8
Invesco
Georgia
$172M -$37.6M -295,350 -18%
Bank of New York Mellon
9
Bank of New York Mellon
New York
$165M -$3.14M -24,697 -2%
Sands Capital Management
10
Sands Capital Management
Virginia
$156M -$5.49M -43,108 -3%
Citadel Advisors
11
Citadel Advisors
Florida
$132M -$33.9M -266,679 -20%
BCM
12
Brown Capital Management
Maryland
$125M +$18M +141,241 +16%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$122M -$1.38M -10,820 -1%
CCA
14
Conestoga Capital Advisors
Pennsylvania
$122M -$425K -3,340 -0.3%
Holocene Advisors
15
Holocene Advisors
New York
$117M -$2.95M -23,168 -2%
AllianceBernstein
16
AllianceBernstein
Tennessee
$113M -$15M -117,787 -12%
Dimensional Fund Advisors
17
Dimensional Fund Advisors
Texas
$95.5M +$6.92M +54,355 +8%
Impax Asset Management Group
18
Impax Asset Management Group
United Kingdom
$93.8M -$5.53M -43,468 -5%
Millennium Management
19
Millennium Management
New York
$87.2M +$86.7M +681,342 +3,424%
New York State Common Retirement Fund
20
New York State Common Retirement Fund
New York
$75.4M -$2.46M -19,352 -3%
DDC
21
DF Dent & Co
Maryland
$72.9M +$1.5M +11,797 +2%
T. Rowe Price Investment Management
22
T. Rowe Price Investment Management
Maryland
$69.6M +$38M +298,731 +115%
Morgan Stanley
23
Morgan Stanley
New York
$65.8M -$7.03M -55,232 -9%
SIMG
24
Stephens Investment Management Group
Texas
$65M -$2.12M -16,695 -3%
ECM
25
ExodusPoint Capital Management
New York
$61.2M +$35.8M +281,668 +134%