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Q32 Bio

54 hedge funds and large institutions have $60.6M invested in Q32 Bio in 2026 Q1 according to their latest regulatory filings, with 12 funds opening new positions, 14 increasing their positions, 9 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

127% more capital invested

Capital invested by funds: $26.7M → $60.6M (+$34M)

56% more repeat investments, than reductions

Existing positions increased: 14 | Existing positions reduced: 9

50% more first-time investments, than exits

New positions opened: 12 | Existing positions closed: 8

4% more funds holding

Funds holding: 5254 (+2)

0% more funds holding in top 10

Funds holding in top 10: 44 (0)

0.92% less ownership

Funds ownership: 65.37%64.46% (-0.92%)

Holders
54
Holders Change
+2
Holders Change %
+3.85%
% of All Funds
0.66%
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
12
Increased
14
Reduced
9
Closed
8
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
O
1
OrbiMed
New York
$14.5M
AVLSA
2
Atlas Venture Life Science Advisors
Massachusetts
$13.4M
OM
3
Opaleye Management
Massachusetts
$8.06M +$4.95M +1,042,865 +489%
CG
4
Carlyle Group
District of Columbia
$7.08M
AVM
5
Arch Venture Management
Illinois
$2.06M
ACA
6
Acorn Capital Advisors
New York
$2.02M -$847K -178,373 -36%
VCM
7
Vanguard Capital Management
Pennsylvania
$1.97M +$1.46M +306,401 New
Mackenzie Financial
8
Mackenzie Financial
Ontario, Canada
$1.58M +$1.17M +246,304 New
S
9
Sanofi
France
$1.57M
Renaissance Technologies
10
Renaissance Technologies
New York
$1.33M +$510K +107,315 +108%
Acadian Asset Management
11
Acadian Asset Management
Massachusetts
$1.11M +$590K +124,213 +257%
MCM
12
Monimus Capital Management
New Jersey
$862K +$638K +134,310 New
Geode Capital Management
13
Geode Capital Management
Massachusetts
$759K +$57.2K +12,039 +11%
P
14
Pfizer
New York
$737K -$837K -176,159 -63%
BlackRock
15
BlackRock
New York
$553K +$125K +26,215 +44%
Jane Street
16
Jane Street
New York
$421K +$191K +40,225 +159%
Marshall Wace
17
Marshall Wace
United Kingdom
$337K +$249K +52,440 New
VFT
18
Vanguard Fiduciary Trust
Pennsylvania
$321K +$238K +49,995 New
Two Sigma Investments
19
Two Sigma Investments
New York
$272K -$21.3K -4,479 -10%
State Street
20
State Street
Massachusetts
$267K +$96.3K +20,277 +95%
Cambridge Investment Research Advisors
21
Cambridge Investment Research Advisors
Iowa
$225K +$166K +35,025 New
ACM
22
ADAR1 Capital Management
Texas
$225K +$71.3K +15,000 +75%
AAA
23
Affinity Asset Advisors
New York
$178K
Northern Trust
24
Northern Trust
Illinois
$161K
Cetera Investment Advisers
25
Cetera Investment Advisers
Illinois
$133K +$98.3K +20,695 New

QTTB Hedge Fund Activity: Q1 2026 in Review

54 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Q32 Bio (QTTB) for Q1 2026, worth a combined $60.6M — up 127% from $26.7M a quarter earlier.

Buyers outnumbered sellers: 12 funds opened new QTTB positions and 8 closed out — a net gain of 4 holders — while 14 added to existing stakes and 9 trimmed.

The largest buyer was Opaleye Management, adding an estimated $4.95M. The largest seller was Acorn Capital Advisors, cutting an estimated $847K.

  • 54 institutional investors held Q32 Bio (QTTB) as of Q1 2026, up from 52 in Q4 2025.
  • Funds reported $60.6M of Q32 Bio stock for Q1 2026, up 127% quarter-over-quarter.
  • 12 funds opened new Q32 Bio positions in Q1 2026 and 8 closed out, a net change of +4 holders.
  • The largest Q32 Bio buyer in Q1 2026 was Opaleye Management, an estimated $4.95M added.
  • The largest Q32 Bio seller in Q1 2026 was Acorn Capital Advisors, an estimated $847K sold.

Based on aggregated 13F filings for Q1 2026.