PolyPid
PYPD
19 hedge funds and large institutions have $13M invested in PolyPid in 2025 Q4 according to their latest regulatory filings, with 5 funds opening new positions, 4 increasing their positions, 5 reducing their positions, and 2 closing their positions.
150% more first-time investments, than exits
New positions opened: 5 | Existing positions closed: 2
38% more capital invested
Capital invested by funds: $9.45M → $13M (+$3.59M)
19% more funds holding
Funds holding: 16 → 19 (+3)
1.07% more ownership
Funds ownership: 17.82% → 18.9% (+1.1%)
0% more funds holding in top 10
Funds holding in top 10: 1 → 1 (0)
20% less repeat investments, than reductions
Existing positions increased: 4 | Existing positions reduced: 5
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
ACM
AIGH Capital Management
Baltimore,
Maryland
|
+$1.03M |
| 2 |
ACM
ADAR1 Capital Management
Austin,
Texas
|
+$386K |
| 3 |
Jane Street
New York
|
+$56.5K |
| 4 |
BRWA
B. Riley Wealth Advisors
Boca Raton,
Florida
|
+$56.2K |
| 5 |
XT
XTX Topco
George Town,
Cayman Islands
|
+$40.4K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
RA
Rosalind Advisors
Toronto,
Ontario, Canada
|
-$825K |
| 2 |
JGC
J. Goldman & Co
New York
|
-$100K |
| 3 |
SPM
Symmetry Peak Management
Radnor,
Pennsylvania
|
-$58.6K |
| 4 |
Goldman Sachs
New York
|
-$47.7K |
| 5 |
BNP Paribas Financial Markets
Paris,
France
|
-$1.69K |
PYPD Hedge Fund Activity: Q4 2025 in Review
19 of the 8,238 institutional investors tracked by Wall St. Rank reported a position in PolyPid (PYPD) for Q4 2025, worth a combined $13M — up 38% from $9.45M a quarter earlier.
Buyers outnumbered sellers: 5 funds opened new PYPD positions and 2 closed out — a net gain of 3 holders — while 4 added to existing stakes and 5 trimmed.
The largest buyer was AIGH Capital Management, adding an estimated $1.03M. The largest seller was Rosalind Advisors, cutting an estimated $825K.
- 19 institutional investors held PolyPid (PYPD) as of Q4 2025, up from 16 in Q3 2025.
- Funds reported $13M of PolyPid stock for Q4 2025, up 38% quarter-over-quarter.
- 5 funds opened new PolyPid positions in Q4 2025 and 2 closed out, a net change of +3 holders.
- The largest PolyPid buyer in Q4 2025 was AIGH Capital Management, an estimated $1.03M added.
- The largest PolyPid seller in Q4 2025 was Rosalind Advisors, an estimated $825K sold.
Based on aggregated 13F filings for Q4 2025.