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Prothena Corp

179 hedge funds and large institutions have $452M invested in Prothena Corp in 2025 Q4 according to their latest regulatory filings, with 24 funds opening new positions, 62 increasing their positions, 57 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

more ownership

Funds ownership:

more capital invested

Capital invested by funds: $ → $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

less first-time investments, than exits

New positions opened: | Existing positions closed:

4% less funds holding

Funds holding: 186179 (-7)

16% less call options, than puts

Call options by funds: $6.74M | Put options by funds: $8.02M

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
179
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$6.74M
Puts
$8.02M
Net Calls
Net Calls Change

Top Buyers

1 +$21.8M
2 +$13.9M
3 +$5.93M
4
BlackRock
BlackRock
New York
+$5.18M
5
Morgan Stanley
Morgan Stanley
New York
+$4.55M
Name Holding Trade Value Shares
Change
Change in
Stake
SO
101
STRS Ohio
Ohio
$168K
AI
102
Atom Investors
Texas
$163K
ET
103
Entropy Technologies
New York
$161K
Raymond James Financial
104
Raymond James Financial
Florida
$157K
Susquehanna International Group
105
Susquehanna International Group
Pennsylvania
$153K
CPIG
106
Chicago Partners Investment Group
Illinois
$152K
Jones Financial Companies
107
Jones Financial Companies
Missouri
$152K
State Board of Administration of Florida Retirement System
108
State Board of Administration of Florida Retirement System
Florida
$147K
Manulife (Manufacturers Life Insurance)
109
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$131K
GLA
110
Great Lakes Advisors
Illinois
$126K
CSP
111
Cary Street Partners
Virginia
$119K
PFSRSONJ
112
Police & Firemen's Retirement System of New Jersey
New Jersey
$119K
Citigroup
113
Citigroup
New York
$118K
BIG
114
Brooklyn Investment Group
New York
$114K
DS
115
DRW Securities
Illinois
$114K
PP
116
PDT Partners
New York
$108K
IC
117
Inscription Capital
Texas
$102K
ProShare Advisors
118
ProShare Advisors
Maryland
$99.6K
Carson Wealth (CWM LLC)
119
Carson Wealth (CWM LLC)
Nebraska
$96K
FRM
120
Fox Run Management
Connecticut
$95.9K
New York State Common Retirement Fund
121
New York State Common Retirement Fund
New York
$85.7K
CUAMC
122
China Universal Asset Management Company
China
$83.8K
Canada Pension Plan Investment Board
123
Canada Pension Plan Investment Board
Ontario, Canada
$67.8K
Public Employees Retirement Association of Colorado
124
Public Employees Retirement Association of Colorado
Colorado
$63K
PWPS
125
Pinnacle Wealth Planning Services
Ohio
$54.1K