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Prothena Corp

181 hedge funds and large institutions have $452M invested in Prothena Corp in 2025 Q4 according to their latest regulatory filings, with 25 funds opening new positions, 62 increasing their positions, 57 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

8.64% more ownership

Funds ownership: 79.15%87.78% (+8.6%)

9% more capital invested

Capital invested by funds: $416M → $452M (+$35.8M)

9% more repeat investments, than reductions

Existing positions increased: 62 | Existing positions reduced: 57

4% less first-time investments, than exits

New positions opened: 25 | Existing positions closed: 26

3% less funds holding

Funds holding: 187181 (-6)

16% less call options, than puts

Call options by funds: $6.74M | Put options by funds: $8.02M

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
181
Holders Change
-6
Holders Change %
-3.21%
% of All Funds
2.2%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
25
Increased
62
Reduced
57
Closed
26
Calls
$6.74M
Puts
$8.02M
Net Calls
-$1.28M
Net Calls Change
+$6.27M
Name Holding Trade Value Shares
Change
Change in
Stake
SO
101
STRS Ohio
Ohio
$168K -$114K -11,200 -39%
AI
102
Atom Investors
Texas
$163K -$43.7K -4,289 -20%
ET
103
Entropy Technologies
New York
$161K +$172K +16,900 New
Raymond James Financial
104
Raymond James Financial
Florida
$157K -$56.5K -5,549 -25%
Susquehanna International Group
105
Susquehanna International Group
Pennsylvania
$153K -$1.44M -141,472 -90%
CPIG
106
Chicago Partners Investment Group
Illinois
$152K +$3.88K +381 +3%
Jones Financial Companies
107
Jones Financial Companies
Missouri
$152K +$19.3K +1,900 +14%
State Board of Administration of Florida Retirement System
108
State Board of Administration of Florida Retirement System
Florida
$147K
Manulife (Manufacturers Life Insurance)
109
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$131K -$1.75K -172 -1%
GLA
110
Great Lakes Advisors
Illinois
$126K -$967 -95 -0.7%
CSP
111
Cary Street Partners
Virginia
$119K
PFSRSONJ
112
Police & Firemen's Retirement System of New Jersey
New Jersey
$119K -$112 -11 -0.1%
Citigroup
113
Citigroup
New York
$118K +$88.8K +8,726 +243%
BIG
114
Brooklyn Investment Group
New York
$114K +$9.51K +934 +8%
DS
115
DRW Securities
Illinois
$114K +$122K +11,955 New
PP
116
PDT Partners
New York
$108K +$115K +11,334 New
IC
117
Inscription Capital
Texas
$102K +$1.75K +172 +2%
ProShare Advisors
118
ProShare Advisors
Maryland
$99.6K +$106K +10,425 New
Carson Wealth (CWM LLC)
119
Carson Wealth (CWM LLC)
Nebraska
$96K -$1.54K -151 -1%
FRM
120
Fox Run Management
Connecticut
$95.9K -$349K -34,287 -77%
New York State Common Retirement Fund
121
New York State Common Retirement Fund
New York
$85.7K
CUAMC
122
China Universal Asset Management Company
China
$83.8K -$6.76K -664 -7%
Canada Pension Plan Investment Board
123
Canada Pension Plan Investment Board
Ontario, Canada
$67.8K +$72.3K +7,100 New
Public Employees Retirement Association of Colorado
124
Public Employees Retirement Association of Colorado
Colorado
$63K
PWPS
125
Pinnacle Wealth Planning Services
Ohio
$54.1K +$57.7K +5,668 New