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Prothena Corp
PRTA

Overview Fund Activity

187 hedge funds and large institutions have $254M invested in Prothena Corp in 2025 Q2 according to their latest regulatory filings, with 52 funds opening new positions, 54 increasing their positions, 41 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
187
Holders Change
+28
Holders Change %
+17.61%
% of All Funds
2.51%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
52
Increased
54
Reduced
41
Closed
22
Calls
$6.7M
Puts
$6.34M
Net Calls
+$359K
Net Calls Change
-$1.89M

Top Buyers

1
ACM
ADAR1 Capital Management
Texas
$20.5M
2
Citadel Advisors
Citadel Advisors
Florida
$6.97M
3
Acadian Asset Management
Acadian Asset Management
Massachusetts
$6.18M
4
Vanguard Group
Vanguard Group
Pennsylvania
$13.2M
5
RC
Rangeley Capital
Connecticut
$4.34M

Top Sellers

1
EC
EcoR1 Capital
California
$0
2
Wellington Management Group
Wellington Management Group
Massachusetts
$655K
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$432K
4
SL
Siren LLC
Connecticut
$0
5
BCM
Boxer Capital Management
California
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
QC
101
Quadrature Capital
United Kingdom
$144K +$144K +23,752 New
NRD
102
Nebula Research & Development
New York
$139K +$139K +22,857 New
Ensign Peak Advisors
103
Ensign Peak Advisors
Utah
$131K – – –
Mirae Asset Global ETFs Holdings
104
Mirae Asset Global ETFs Holdings
Hong Kong
$129K -$37.1K -6,116 -22%
Handelsbanken Fonder
105
Handelsbanken Fonder
Sweden
$127K – – –
MJRIC
106
Mogy Joel R Investment Counsel
California
$126K +$126K +20,750 New
FWMM
107
Foundation Wealth Management (Missouri)
Missouri
$118K – – –
Connor, Clark & Lunn Investment Management (CC&L)
108
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$115K -$441K -72,586 -79%
OC
109
Oppenheimer & Co
New York
$113K +$113K +18,595 New
VIA
110
Virtus Investment Advisers
Connecticut
$113K +$40.4K +6,656 +56%
VCM
111
Voleon Capital Management
California
$113K +$113K +18,536 New
IIM
112
INTECH Investment Management
Florida
$112K -$91.1K -15,001 -45%
JG
113
Jain Global
New York
$111K +$111K +18,262 New
Janus Henderson Group
114
Janus Henderson Group
United Kingdom
$110K – – –
PNC Financial Services Group
115
PNC Financial Services Group
Pennsylvania
$109K +$106K +17,540 +3,594%
Los Angeles Capital Management
116
Los Angeles Capital Management
California
$101K +$101K +16,702 New
CPIG
117
Chicago Partners Investment Group
Illinois
$99.8K +$1.67K +247 +2%
SO
118
STRS Ohio
Ohio
$99.5K +$99.5K +16,400 New
Zurich Cantonal Bank
119
Zurich Cantonal Bank
Switzerland
$94.5K -$2.87K -472 -3%
State Board of Administration of Florida Retirement System
120
State Board of Administration of Florida Retirement System
Florida
$93.4K – – –
SCM
121
Shelton Capital Management
Colorado
$92.7K +$279 +46 +0.3%
Manulife (Manufacturers Life Insurance)
122
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$91.9K -$304K -50,091 -77%
Jones Financial Companies
123
Jones Financial Companies
Missouri
$85.1K +$85.1K +14,000 New
CC
124
Corton Capital
Ontario, Canada
$84.8K +$84.8K +13,964 New
DekaBank Deutsche Girozentrale
125
DekaBank Deutsche Girozentrale
Germany
$84K – – –
3 4
5
6 7