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Prothena Corp

179 hedge funds and large institutions have $452M invested in Prothena Corp in 2025 Q4 according to their latest regulatory filings, with 24 funds opening new positions, 62 increasing their positions, 57 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

more ownership

Funds ownership:

more capital invested

Capital invested by funds: $ → $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

less first-time investments, than exits

New positions opened: | Existing positions closed:

4% less funds holding

Funds holding: 186179 (-7)

16% less call options, than puts

Call options by funds: $6.74M | Put options by funds: $8.02M

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
179
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$6.74M
Puts
$8.02M
Net Calls
Net Calls Change

Top Buyers

1 +$21.8M
2 +$13.9M
3 +$5.93M
4
BlackRock
BlackRock
New York
+$5.18M
5
Morgan Stanley
Morgan Stanley
New York
+$4.55M
Name Holding Trade Value Shares
Change
Change in
Stake
DekaBank Deutsche Girozentrale
76
DekaBank Deutsche Girozentrale
Germany
$383K
Deutsche Bank
77
Deutsche Bank
Germany
$339K
QC
78
Quadrature Capital
United Kingdom
$297K
PA
79
Profund Advisors
Maryland
$292K
RC
80
RBF Capital
California
$279K
PAP
81
Persistent Asset Partners
Hong Kong
$273K
PNC Financial Services Group
82
PNC Financial Services Group
Pennsylvania
$269K
GCM
83
Graham Capital Management
Connecticut
$265K
HSBC Holdings
84
HSBC Holdings
United Kingdom
$261K
Invesco
85
Invesco
Georgia
$254K
Tudor Investment Corp
86
Tudor Investment Corp
Connecticut
$253K
GCP
87
GSA Capital Partners
United Kingdom
$252K
VIA
88
Virtus Investment Advisers
Connecticut
$245K
MIM
89
MetLife Investment Management
New Jersey
$244K
Mirae Asset Global ETFs Holdings
90
Mirae Asset Global ETFs Holdings
Hong Kong
$240K
PCA
91
Purkiss Capital Advisors
Connecticut
$240K
Edgewood Management
92
Edgewood Management
Connecticut
$230K
PCM
93
Polymer Capital Management
New York
$225K
HT
94
Headlands Technologies
Illinois
$223K
Millennium Management
95
Millennium Management
New York
$210K
C
96
Covestor
United Kingdom
$208K
MJRIC
97
Mogy Joel R Investment Counsel
California
$198K
IIM
98
INTECH Investment Management
Florida
$197K
TI
99
Trexquant Investment
Connecticut
$185K
BP
100
Ballentine Partners
Massachusetts
$173K