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Prothena Corp

181 hedge funds and large institutions have $452M invested in Prothena Corp in 2025 Q4 according to their latest regulatory filings, with 25 funds opening new positions, 62 increasing their positions, 57 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

8.64% more ownership

Funds ownership: 79.15%87.78% (+8.6%)

9% more capital invested

Capital invested by funds: $416M → $452M (+$35.8M)

9% more repeat investments, than reductions

Existing positions increased: 62 | Existing positions reduced: 57

4% less first-time investments, than exits

New positions opened: 25 | Existing positions closed: 26

3% less funds holding

Funds holding: 187181 (-6)

16% less call options, than puts

Call options by funds: $6.74M | Put options by funds: $8.02M

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
181
Holders Change
-6
Holders Change %
-3.21%
% of All Funds
2.2%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
25
Increased
62
Reduced
57
Closed
26
Calls
$6.74M
Puts
$8.02M
Net Calls
-$1.28M
Net Calls Change
+$6.27M
Name Holding Trade Value Shares
Change
Change in
Stake
DekaBank Deutsche Girozentrale
76
DekaBank Deutsche Girozentrale
Germany
$383K
Deutsche Bank
77
Deutsche Bank
Germany
$339K +$17.4K +1,709 +5%
QC
78
Quadrature Capital
United Kingdom
$297K +$39.4K +3,875 +14%
PA
79
Profund Advisors
Maryland
$292K +$312K +30,616 New
RC
80
RBF Capital
California
$279K
PAP
81
Persistent Asset Partners
Hong Kong
$273K +$291K +28,589 New
PNC Financial Services Group
82
PNC Financial Services Group
Pennsylvania
$269K +$102K +9,991 +55%
GCM
83
Graham Capital Management
Connecticut
$265K -$261K -25,637 -48%
HSBC Holdings
84
HSBC Holdings
United Kingdom
$261K -$98.7K -9,699 -26%
Invesco
85
Invesco
Georgia
$254K -$47.8K -4,694 -15%
Tudor Investment Corp
86
Tudor Investment Corp
Connecticut
$253K -$6.11K -600 -2%
GCP
87
GSA Capital Partners
United Kingdom
$252K +$268K +26,354 New
VIA
88
Virtus Investment Advisers
Connecticut
$245K +$32.9K +3,236 +14%
MIM
89
MetLife Investment Management
New Jersey
$244K +$62.5K +6,139 +32%
Mirae Asset Global ETFs Holdings
90
Mirae Asset Global ETFs Holdings
Hong Kong
$240K +$65.2K +6,406 +34%
PCA
91
Purkiss Capital Advisors
Connecticut
$240K -$3.05K -300 -1%
Edgewood Management
92
Edgewood Management
Connecticut
$230K
PCM
93
Polymer Capital Management
New York
$225K +$239K +23,513 New
HT
94
Headlands Technologies
Illinois
$223K +$238K +23,352 New
Millennium Management
95
Millennium Management
New York
$210K -$6.1M -599,123 -96%
C
96
Covestor
United Kingdom
$208K -$98.1K -9,639 -31%
MJRIC
97
Mogy Joel R Investment Counsel
California
$198K
IIM
98
INTECH Investment Management
Florida
$197K +$12.3K +1,213 +6%
TI
99
Trexquant Investment
Connecticut
$185K -$2.64M -259,595 -93%
BP
100
Ballentine Partners
Massachusetts
$173K -$2.44K -240 -1%