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Prothena Corp
PRTA

Overview Fund Activity

159 hedge funds and large institutions have $647M invested in Prothena Corp in 2025 Q1 according to their latest regulatory filings, with 17 funds opening new positions, 42 increasing their positions, 58 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
159
Holders Change
-10
Holders Change %
-5.92%
% of All Funds
2.16%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
17
Increased
42
Reduced
58
Closed
25
Calls
$3.5M
Puts
$1.25M
Net Calls
+$2.25M
Net Calls Change
-$2.23M

Top Buyers

1
Nordea Investment Management
Nordea Investment Management
Sweden
+$3.74M
2
SL
Siren LLC
Connecticut
+$2.27M
3
DA
DCF Advisers
Connecticut
+$1.13M
4
Jane Street
Jane Street
New York
+$954K
5
Wellington Management Group
Wellington Management Group
Massachusetts
+$850K

Top Sellers

1
State Street
State Street
Massachusetts
-$4.21M
2
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$2.84M
3
Federated Hermes
Federated Hermes
Pennsylvania
-$2.47M
4
RSCM
Rock Springs Capital Management
Maryland
-$1.88M
5
Axa
Axa
France
-$1.67M
Name Holding Trade Value Shares
Change 		Shares
Change %
Jacobs Levy Equity Management
76
Jacobs Levy Equity Management
New Jersey
$230K +$230K +18,553 New
D.E. Shaw & Co
77
D.E. Shaw & Co
New York
$220K +$220K +17,803 New
Man Group
78
Man Group
United Kingdom
$210K -$748K -60,430 -78%
Zurich Cantonal Bank
79
Zurich Cantonal Bank
Switzerland
$198K +$124 +10 +0.1%
Two Sigma Investments
80
Two Sigma Investments
New York
$198K -$277K -22,361 -58%
State Board of Administration of Florida Retirement System
81
State Board of Administration of Florida Retirement System
Florida
$190K – – –
SCM
82
Shelton Capital Management
Colorado
$189K +$189K +15,233 New
DekaBank Deutsche Girozentrale
83
DekaBank Deutsche Girozentrale
Germany
$180K – – –
New York State Common Retirement Fund
84
New York State Common Retirement Fund
New York
$177K – – –
HF
85
HRT Financial
New York
$173K +$173K +14,036 New
Commonwealth Equity Services
86
Commonwealth Equity Services
Massachusetts
$165K +$165K +13,320 New
CAM
87
Cresset Asset Management
Illinois
$162K -$78.1K -6,309 -32%
HSBC Holdings
88
HSBC Holdings
United Kingdom
$160K -$135K -11,091 -46%
CSP
89
Cary Street Partners
Virginia
$155K – – –
Raymond James Financial
90
Raymond James Financial
Florida
$155K -$7.72K -624 -5%
VIA
91
Virtus Investment Advisers
Connecticut
$147K +$147K +11,891 New
VOYA Investment Management
92
VOYA Investment Management
Georgia
$145K -$14.2K -1,145 -9%
ProShare Advisors
93
ProShare Advisors
Maryland
$144K -$35.8K -2,892 -20%
CUAMC
94
China Universal Asset Management Company
China
$134K -$7.57K -612 -5%
Creative Planning
95
Creative Planning
Kansas
$132K -$66.5K -5,371 -33%
Cambridge Investment Research Advisors
96
Cambridge Investment Research Advisors
Iowa
$126K +$126K +10,164 New
PFSRSONJ
97
Police & Firemen's Retirement System of New Jersey
New Jersey
$125K – – –
BNP Paribas Financial Markets
98
BNP Paribas Financial Markets
France
$119K -$1.09M -87,806 -90%
CPIG
99
Chicago Partners Investment Group
Illinois
$106K +$24.2K +3,315 +30%
KK
100
KLP Kapitalforvaltning
Norway
$82.9K -$76.7K -6,200 -48%
2 3
4
5 6