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Prothena Corp
PRTA

Overview Fund Activity

187 hedge funds and large institutions have $254M invested in Prothena Corp in 2025 Q2 according to their latest regulatory filings, with 52 funds opening new positions, 54 increasing their positions, 41 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
187
Holders Change
+28
Holders Change %
+17.61%
% of All Funds
2.51%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
52
Increased
54
Reduced
41
Closed
22
Calls
$6.7M
Puts
$6.34M
Net Calls
+$359K
Net Calls Change
-$1.89M

Top Buyers

1
ACM
ADAR1 Capital Management
Texas
+$20.5M
2
Citadel Advisors
Citadel Advisors
Florida
+$6.42M
3
Acadian Asset Management
Acadian Asset Management
Massachusetts
+$6.18M
4
Vanguard Group
Vanguard Group
Pennsylvania
+$5.51M
5
RC
Rangeley Capital
Connecticut
+$4.34M

Top Sellers

1
EC
EcoR1 Capital
California
-$143M
2
Wellington Management Group
Wellington Management Group
Massachusetts
-$30.9M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$20.6M
4
SL
Siren LLC
Connecticut
-$15.9M
5
BCM
Boxer Capital Management
California
-$8.54M
Name Holding Trade Value Shares
Change 		Shares
Change %
Renaissance Technologies
51
Renaissance Technologies
New York
$548K -$909K -149,700 -62%
DWAM
52
Duncan Williams Asset Management
Tennessee
$536K – – –
AllianceBernstein
53
AllianceBernstein
Tennessee
$532K +$248K +40,834 +87%
HWAM
54
Hennion & Walsh Asset Management
New Jersey
$523K +$51.7K +8,517 +11%
PA
55
Pinnacle Associates
New York
$450K -$159K -26,180 -26%
SPS
56
Susquehanna Portfolio Strategies
Pennsylvania
$435K +$435K +71,668 New
T. Rowe Price Associates
57
T. Rowe Price Associates
Maryland
$432K -$20.6M -3,384,809 -98%
MAM
58
Monaco Asset Management
Monaco
$425K +$425K +70,000 New
CM
59
Caption Management
Oklahoma
$395K +$395K +65,100 New
RhumbLine Advisers
60
RhumbLine Advisers
Massachusetts
$382K -$18.7K -3,074 -5%
UBS Group
61
UBS Group
Switzerland
$368K -$1.12M -183,815 -75%
American Century Companies
62
American Century Companies
Missouri
$364K +$153K +25,129 +72%
QCM
63
Quantinno Capital Management
New York
$362K +$362K +59,618 New
ECM
64
ExodusPoint Capital Management
New York
$358K +$107K +17,646 +43%
Norges Bank
65
Norges Bank
Norway
$349K +$349K +57,454 New
Swiss National Bank
66
Swiss National Bank
Switzerland
$343K -$74.1K -12,200 -18%
Franklin Resources
67
Franklin Resources
California
$340K +$221K +36,331 +184%
SG Americas Securities
68
SG Americas Securities
New York
$315K -$125K -20,618 -28%
Creative Planning
69
Creative Planning
Kansas
$307K +$242K +39,879 +373%
QOP
70
Quinn Opportunity Partners
Virginia
$304K +$304K +50,000 New
Citigroup
71
Citigroup
New York
$299K -$100K -16,523 -25%
AG
72
Algert Global
California
$292K +$292K +48,150 New
BNP Paribas Financial Markets
73
BNP Paribas Financial Markets
France
$284K +$226K +37,267 +389%
HSBC Holdings
74
HSBC Holdings
United Kingdom
$282K +$202K +32,959 +252%
Massachusetts Financial Services
75
Massachusetts Financial Services
Massachusetts
$269K +$3.33K +548 +1%
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