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Prothena Corp
PRTA

Overview Fund Activity

187 hedge funds and large institutions have $254M invested in Prothena Corp in 2025 Q2 according to their latest regulatory filings, with 52 funds opening new positions, 54 increasing their positions, 41 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
187
Holders Change
+28
Holders Change %
+17.61%
% of All Funds
2.51%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
52
Increased
54
Reduced
41
Closed
22
Calls
$6.7M
Puts
$6.34M
Net Calls
+$359K
Net Calls Change
-$1.89M

Top Buyers

1
ACM
ADAR1 Capital Management
Texas
$20.5M
2
Citadel Advisors
Citadel Advisors
Florida
$6.97M
3
Acadian Asset Management
Acadian Asset Management
Massachusetts
$6.18M
4
Vanguard Group
Vanguard Group
Pennsylvania
$13.2M
5
RC
Rangeley Capital
Connecticut
$4.34M

Top Sellers

1
EC
EcoR1 Capital
California
$0
2
Wellington Management Group
Wellington Management Group
Massachusetts
$655K
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$432K
4
SL
Siren LLC
Connecticut
$0
5
BCM
Boxer Capital Management
California
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
Northern Trust
26
Northern Trust
Illinois
$2.03M -$238K -39,149 -10%
Nordea Investment Management
27
Nordea Investment Management
Sweden
$1.92M +$22.3K +3,618 +1%
SSA
28
Schonfeld Strategic Advisors
New York
$1.87M +$1.87M +307,341 New
Charles Schwab
29
Charles Schwab
California
$1.67M -$270K -44,523 -14%
PM
30
Prosight Management
Texas
$1.63M -$852K -140,322 -34%
Bank of America
31
Bank of America
North Carolina
$1.28M +$479K +78,959 +60%
GCP
32
GSA Capital Partners
United Kingdom
$1.28M +$1.28M +210,555 New
Squarepoint
33
Squarepoint
New York
$1.27M +$1.27M +209,249 New
MCM
34
Monimus Capital Management
New Jersey
$1.25M +$1.25M +206,475 New
Two Sigma Investments
35
Two Sigma Investments
New York
$1.22M +$1.13M +185,417 +1,156%
Millennium Management
36
Millennium Management
New York
$1.04M +$717K +118,112 +225%
DA
37
DCF Advisers
Connecticut
$950K -$234K -38,500 -20%
Ameriprise
38
Ameriprise
Minnesota
$920K +$920K +151,543 New
Bank of New York Mellon
39
Bank of New York Mellon
New York
$900K +$14.2K +2,341 +2%
Two Sigma Advisers
40
Two Sigma Advisers
New York
$849K +$849K +139,800 New
UBS AM
41
UBS AM
Illinois
$845K -$1.47M -242,368 -64%
JPMorgan Chase & Co
42
JPMorgan Chase & Co
New York
$771K -$1.49M -245,014 -66%
NL
43
Nuveen LLC
North Carolina
$741K -$169K -27,806 -19%
Jane Street
44
Jane Street
New York
$713K -$92.2K -15,187 -11%
Barclays
45
Barclays
United Kingdom
$704K +$197K +32,467 +39%
Wellington Management Group
46
Wellington Management Group
Massachusetts
$655K -$30.9M -5,091,689 -98%
Royal Bank of Canada
47
Royal Bank of Canada
Ontario, Canada
$643K +$617K +101,621 +2,353%
State of Wisconsin Investment Board
48
State of Wisconsin Investment Board
Wisconsin
$631K +$631K +103,996 New
Russell Investments Group
49
Russell Investments Group
United Kingdom
$584K +$577K +95,002 +7,957%
Susquehanna International Group
50
Susquehanna International Group
Pennsylvania
$558K +$89.3K +14,707 +19%
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