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Prothena Corp
PRTA

Overview Fund Activity

159 hedge funds and large institutions have $647M invested in Prothena Corp in 2025 Q1 according to their latest regulatory filings, with 17 funds opening new positions, 42 increasing their positions, 58 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
159
Holders Change
-10
Holders Change %
-5.92%
% of All Funds
2.16%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
17
Increased
42
Reduced
58
Closed
25
Calls
$3.5M
Puts
$1.25M
Net Calls
+$2.25M
Net Calls Change
-$2.23M

Top Buyers

1
Nordea Investment Management
Nordea Investment Management
Sweden
+$3.74M
2
SL
Siren LLC
Connecticut
+$2.27M
3
DA
DCF Advisers
Connecticut
+$1.13M
4
Jane Street
Jane Street
New York
+$954K
5
Wellington Management Group
Wellington Management Group
Massachusetts
+$850K

Top Sellers

1
State Street
State Street
Massachusetts
-$4.21M
2
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$2.84M
3
Federated Hermes
Federated Hermes
Pennsylvania
-$2.47M
4
RSCM
Rock Springs Capital Management
Maryland
-$1.88M
5
Axa
Axa
France
-$1.67M
Name Holding Trade Value Shares
Change 		Shares
Change %
Nordea Investment Management
26
Nordea Investment Management
Sweden
$3.74M +$3.74M +307,987 New
UBS Group
27
UBS Group
Switzerland
$3.03M -$1.57M -126,808 -34%
Renaissance Technologies
28
Renaissance Technologies
New York
$2.97M +$470K +38,000 +19%
DA
29
DCF Advisers
Connecticut
$2.41M +$1.13M +91,500 +88%
PP
30
PDT Partners
New York
$1.86M +$286K +23,113 +18%
NL
31
Nuveen LLC
North Carolina
$1.86M +$1.86M +149,961 New
Bank of New York Mellon
32
Bank of New York Mellon
New York
$1.81M -$52.3K -4,229 -3%
Jane Street
33
Jane Street
New York
$1.64M +$954K +77,112 +139%
Bank of America
34
Bank of America
North Carolina
$1.63M +$161K +12,979 +11%
PA
35
Pinnacle Associates
New York
$1.24M -$34.9K -2,822 -3%
Deutsche Bank
36
Deutsche Bank
Germany
$1.19M -$1.98K -160 -0.2%
Connor, Clark & Lunn Investment Management (CC&L)
37
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$1.13M -$4.43K -358 -0.4%
Citadel Advisors
38
Citadel Advisors
Florida
$1.11M +$593K +47,881 +115%
DWAM
39
Duncan Williams Asset Management
Tennessee
$1.09M +$237K +19,140 +28%
Barclays
40
Barclays
United Kingdom
$1.03M -$271K -21,957 -21%
HWAM
41
Hennion & Walsh Asset Management
New Jersey
$961K +$314K +25,353 +48%
Susquehanna International Group
42
Susquehanna International Group
Pennsylvania
$956K +$643K +51,974 +206%
SFI
43
Susquehanna Fundamental Investments
Pennsylvania
$925K -$73.1K -5,905 -7%
SG Americas Securities
44
SG Americas Securities
New York
$898K +$433K +34,947 +93%
Swiss National Bank
45
Swiss National Bank
Switzerland
$850K – – –
RhumbLine Advisers
46
RhumbLine Advisers
Massachusetts
$818K -$12.8K -1,036 -2%
Citigroup
47
Citigroup
New York
$815K -$32.3K -2,607 -4%
Manulife (Manufacturers Life Insurance)
48
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$807K -$61.3K -4,953 -7%
TD Asset Management
49
TD Asset Management
Ontario, Canada
$776K -$24.8K -2,000 -3%
Millennium Management
50
Millennium Management
New York
$649K -$873K -70,538 -57%
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