|
1
|
New Leaf Venture Partners
New York
|
$76.7M
|
+$74.1M
|
+2,625,713
|
New
|
|
|
2
|
|
$76.1M
|
+$73.5M
|
+2,605,713
|
New
|
|
|
3
|
Sofinnova Investments
Menlo Park,
California
|
$59.6M
|
+$58.1M
|
+2,059,146
|
New
|
|
|
4
|
Baker Bros. Advisors
New York
|
$52.2M
|
+$50.5M
|
+1,787,807
|
New
|
|
|
5
|
Cormorant Asset Management
Boston,
Massachusetts
|
$43.4M
|
+$42M
|
+1,486,898
|
New
|
|
|
6
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$25.3M
|
+$24.5M
|
+867,059
|
New
|
|
|
7
|
Fidelity Investments
Boston,
Massachusetts
|
$20.7M
|
+$20M
|
+708,877
|
New
|
|
|
8
|
|
$17.4M
|
+$18.2M
|
+644,448
|
New
|
|
|
9
|
Wellington Management Group
Boston,
Massachusetts
|
$10M
|
+$9.7M
|
+343,736
|
New
|
|
|
10
|
Adage Capital Partners
Boston,
Massachusetts
|
$8.77M
|
+$8.47M
|
+300,000
|
New
|
|
|
11
|
Driehaus Capital Management
Chicago,
Illinois
|
$7.26M
|
+$7.02M
|
+248,626
|
New
|
|
|
12
|
BVF Inc
San Francisco,
California
|
$7.01M
|
+$6.77M
|
+240,000
|
New
|
|
|
13
|
Massachusetts Financial Services
Boston,
Massachusetts
|
$6.59M
|
+$6.37M
|
+225,562
|
New
|
|
|
14
|
Franklin Resources
San Mateo,
California
|
$6.58M
|
+$6.35M
|
+225,000
|
New
|
|
|
15
|
|
$4.38M
|
+$4.23M
|
+150,000
|
New
|
|
|
16
|
|
$4.37M
|
+$4.22M
|
+149,500
|
New
|
|
|
17
|
Millennium Management
New York
|
$4.15M
|
+$4.01M
|
+141,925
|
New
|
|
|
18
|
Farallon Capital Management
San Francisco,
California
|
$3.65M
|
+$3.53M
|
+125,000
|
New
|
|
|
19
|
Oxford Asset Management
Oxford,
United Kingdom
|
$3.23M
|
+$3.14M
|
+111,343
|
New
|
|
|
20
|
Alyeska Investment Group
Chicago,
Illinois
|
$2.92M
|
+$2.82M
|
+100,000
|
New
|
|
|
21
|
Laurion Capital Management
New York
|
$2.92M
|
+$2.82M
|
+100,000
|
New
|
|
|
22
|
Polar Capital
London,
United Kingdom
|
$2.92M
|
+$2.82M
|
+100,000
|
New
|
|
|
23
|
American Century Companies
Kansas City,
Missouri
|
$2.86M
|
+$2.76M
|
+97,772
|
New
|
|
|
24
|
Vanguard Group
Malvern,
Pennsylvania
|
$2.75M
|
+$2.65M
|
+93,943
|
New
|
|
|
25
|
|
$2.28M
|
+$2.2M
|
+77,896
|
New
|
|