Precigen
PGEN
179 hedge funds and large institutions have $569M invested in Precigen in 2025 Q4 according to their latest regulatory filings, with 36 funds opening new positions, 78 increasing their positions, 32 reducing their positions, and 19 closing their positions.
1,224% more call options, than puts
Call options by funds: $12.4M | Put options by funds: $938K
144% more repeat investments, than reductions
Existing positions increased: 78 | Existing positions reduced: 32
100% more funds holding in top 10
Funds holding in top 10: 2 → 4 (+2)
89% more first-time investments, than exits
New positions opened: 36 | Existing positions closed: 19
55% more capital invested
Capital invested by funds: $366M → $569M (+$202M)
7% more funds holding
Funds holding: 167 → 179 (+12)
1.09% more ownership
Funds ownership: 37.35% → 38.44% (+1.1%)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Point72 Asset Management
Stamford,
Connecticut
|
+$42.5M |
| 2 |
State Street
Boston,
Massachusetts
|
+$24.5M |
| 3 |
Fidelity Investments
Boston,
Massachusetts
|
+$17.5M |
| 4 |
BlackRock
New York
|
+$11.4M |
| 5 |
DC
Diametric Capital
Boston,
Massachusetts
|
+$11.1M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
PCM
Patient Capital Management
Baltimore,
Maryland
|
-$30.1M |
| 2 |
TCM
Tang Capital Management
San Diego,
California
|
-$26.2M |
| 3 |
PHP
Parkman Healthcare Partners
Stamford,
Connecticut
|
-$4.25M |
| 4 |
SSA
Schonfeld Strategic Advisors
New York
|
-$2.82M |
| 5 |
Millennium Management
New York
|
-$2.56M |
PGEN Hedge Fund Activity: Q4 2025 in Review
179 of the 8,263 institutional investors tracked by Wall St. Rank reported a position in Precigen (PGEN) for Q4 2025, worth a combined $569M — up 55% from $366M a quarter earlier.
Buyers outnumbered sellers: 36 funds opened new PGEN positions and 19 closed out — a net gain of 17 holders — while 78 added to existing stakes and 32 trimmed.
The largest buyer was Point72 Asset Management, adding an estimated $42.5M. The largest seller was Patient Capital Management, cutting an estimated $30.1M.
- 179 institutional investors held Precigen (PGEN) as of Q4 2025, up from 167 in Q3 2025.
- Funds reported $569M of Precigen stock for Q4 2025, up 55% quarter-over-quarter.
- 36 funds opened new Precigen positions in Q4 2025 and 19 closed out, a net change of +17 holders.
- The largest Precigen buyer in Q4 2025 was Point72 Asset Management, an estimated $42.5M added.
- The largest Precigen seller in Q4 2025 was Patient Capital Management, an estimated $30.1M sold.
Based on aggregated 13F filings for Q4 2025.