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2,952 hedge funds and large institutions have $106B invested in Pfizer in 2026 Q1 according to their latest regulatory filings, with 256 funds opening new positions, 1,303 increasing their positions, 1,088 reducing their positions, and 167 closing their positions.

New
Increased
Maintained
Reduced
Closed

53% more first-time investments, than exits

New positions opened: 256 | Existing positions closed: 167

52% more funds holding in top 10

Funds holding in top 10: 3147 (+16)

20% more repeat investments, than reductions

Existing positions increased: 1,303 | Existing positions reduced: 1,088

15% more call options, than puts

Call options by funds: $3.08B | Put options by funds: $2.68B

14% more capital invested

Capital invested by funds: $93B → $106B (+$12.6B)

1% more funds holding

Funds holding: 2,9132,952 (+39)

0.46% more ownership

Funds ownership: 65.68%66.15% (+0.46%)

Holders
2,952
Holders Change
+39
Holders Change %
+1.34%
% of All Funds
36.12%
Holding in Top 10
47
Holding in Top 10 Change
+16
Holding in Top 10 Change %
+51.61%
% of All Funds
0.58%
New
256
Increased
1,303
Reduced
1,088
Closed
167
Calls
$3.08B
Puts
$2.68B
Net Calls
+$400M
Net Calls Change
+$993M
Name Holding Trade Value Shares
Change
Change in
Stake
SO
176
STRS Ohio
Ohio
$57.4M -$3.44M -129,035 -6%
FWIA
177
Fort Washington Investment Advisors
Ohio
$57.3M +$2.74M +103,010 +5%
SCA
178
STALEY CAPITAL ADVISERS
Pennsylvania
$57.2M +$1.44M +54,140 +3%
WP
179
Woodline Partners
California
$57.1M +$10.8M +405,567 +25%
AH
180
Allen Holding
New York
$56.2M +$12.8M +480,200 +32%
CS
181
Candriam SCA
Luxembourg
$56M +$528K +19,837 +1%
CIC
182
Crawford Investment Counsel
Georgia
$55.9M -$2.42M -91,017 -4%
Rockefeller Capital Management
183
Rockefeller Capital Management
New York
$55.7M +$3.8M +142,551 +8%
DnB Asset Management
184
DnB Asset Management
Norway
$55.2M +$5.65M +212,096 +12%
ORIO
185
Old Republic International (ORI)
Illinois
$55.1M
KAS
186
Kestra Advisory Services
Texas
$54.9M +$6.64M +249,309 +15%
O
187
OrbiMed
New York
$54.7M +$7.82M +293,600 +18%
State of New Jersey Common Pension Fund D
188
State of New Jersey Common Pension Fund D
New Jersey
$54.6M -$593K -22,286 -1%
RAM
189
Resona Asset Management
Japan
$54.2M +$371K +13,944 +0.7%
CCM
190
Causeway Capital Management
California
$53.8M -$4.73M -177,500 -8%
N
191
Natixis
France
$53.7M -$99M -3,717,590 -66%
TI
192
Tidal Investments
Wisconsin
$53.7M +$37.7M +1,414,258 +277%
Jane Street
193
Jane Street
New York
$52.9M +$33.4M +1,255,392 +200%
Mariner
194
Mariner
Kansas
$52.3M +$3.41M +127,917 +7%
QCM
195
Quantinno Capital Management
New York
$52.1M +$4.67M +175,560 +10%
CAI
196
Capital Advisors Inc
Oklahoma
$51.2M +$4.85M +182,048 +11%
Calamos Advisors
197
Calamos Advisors
Illinois
$50.7M -$3.02M -113,617 -6%
CIBC Asset Management
198
CIBC Asset Management
Ontario, Canada
$50.4M +$5.54M +208,006 +13%
Cambridge Investment Research Advisors
199
Cambridge Investment Research Advisors
Iowa
$50.3M -$798K -29,983 -2%
TAM
200
Talaria Asset Management
Australia
$50M

PFE Hedge Fund Activity: Q1 2026 in Review

2,952 of the 8,172 institutional investors tracked by Wall St. Rank reported a position in Pfizer (PFE) for Q1 2026, worth a combined $106B — up 14% from $93B a quarter earlier.

Buyers outnumbered sellers: 256 funds opened new PFE positions and 167 closed out — a net gain of 89 holders — while 1,303 added to existing stakes and 1,088 trimmed.

The largest buyer was Fisher Asset Management, adding an estimated $1.41B. The largest seller was BNP Paribas Financial Markets, cutting an estimated $176M.

  • 2,952 institutional investors held Pfizer (PFE) as of Q1 2026, up from 2,913 in Q4 2025.
  • Funds reported $106B of Pfizer stock for Q1 2026, up 14% quarter-over-quarter.
  • 256 funds opened new Pfizer positions in Q1 2026 and 167 closed out, a net change of +89 holders.
  • The largest Pfizer buyer in Q1 2026 was Fisher Asset Management, an estimated $1.41B added.
  • The largest Pfizer seller in Q1 2026 was BNP Paribas Financial Markets, an estimated $176M sold.

Based on aggregated 13F filings for Q1 2026.