D.E. Shaw & Co’s Pfizer PFE Stock Holding History

D.E. Shaw & Co’s Portfolio PFE Stock Details PFE Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$350M	Buy	12,467,262 +9,051,769	+265%	+$241M	0.21%	89
2025 Q4	$85M	Sell	3,415,493 -2,488,305	-42%	-$62.7M	0.05%	464
2025 Q3	$150M	Buy	5,903,798 +2,154,868	+57%	+$53.2M	0.08%	272
2025 Q2	$90.9M	Sell	3,748,930 -2,245,534	-37%	-$52.4M	0.06%	356
2025 Q1	$152M	Sell	5,994,464 -1,712,316	-22%	-$44.8M	0.14%	170
2024 Q4	$204M	Buy	7,706,780 +2,186,095	+40%	+$59.3M	0.15%	144
2024 Q3	$160M	Sell	5,520,685 -2,904,036	-34%	-$84.7M	0.14%	163
2024 Q2	$236M	Sell	8,424,721 -15,868,198	-65%	-$437M	0.22%	93
2024 Q1	$674M	Buy	24,292,919 +9,770,933	+67%	+$271M	0.58%	14
2023 Q4	$418M	Buy	14,521,986 +1,369,112	+10%	+$41.4M	0.37%	34
2023 Q3	$436M	Buy	13,152,874 +6,675,541	+103%	+$236M	0.46%	21
2023 Q2	$238M	Sell	6,477,333 -1,141,180	-15%	-$44.4M	0.24%	68
2023 Q1	$311M	Buy	7,618,513 +361,509	+5%	+$15.6M	0.33%	30
2022 Q4	$372M	Buy	7,257,004 +4,402,503	+154%	+$211M	0.41%	16
2022 Q3	$125M	Sell	2,854,501 -27,604	-1%	-$1.34M	0.15%	126
2022 Q2	$151M	Sell	2,882,105 -6,973,010	-71%	-$355M	0.18%	96
2022 Q1	$510M	Buy	9,855,115 +6,533,107	+197%	+$339M	0.48%	11
2021 Q4	$196M	Sell	3,322,008 -1,160,547	-26%	-$57.5M	0.16%	114
2021 Q3	$193M	Sell	4,482,555 -1,541,261	-26%	-$68.3M	0.17%	102
2021 Q2	$236M	Buy	6,023,816 +4,572,946	+315%	+$178M	0.2%	83
2021 Q1	$52.6M	Sell	1,450,870 -299,828	-17%	-$10.6M	0.05%	473
2020 Q4	$64.4M	Sell	1,750,698 -4,633,465	-73%	-$170M	0.06%	400
2020 Q3	$222M	Sell	6,384,163 -3,894,200	-38%	-$137M	0.23%	75
2020 Q2	$319M	Sell	10,278,363 -2,102,903	-17%	-$71.4M	0.38%	32
2020 Q1	$383M	Buy	12,381,266 +8,788,705	+245%	+$299M	0.6%	13
2019 Q4	$134M	Buy	3,592,561 +143,035	+4%	+$5.09M	0.15%	154
2019 Q3	$118M	Sell	3,449,526 -291,714	-8%	-$10.6M	0.14%	149
2019 Q2	$154M	Sell	3,741,240 -7,696,994	-67%	-$306M	0.19%	106
2019 Q1	$461M	Buy	11,438,234 +10,886,229	+1,972%	+$436M	0.6%	14
2018 Q4	$22.9M	Buy	552,005 +171,471	+45%	+$7.12M	0.03%	653
2018 Q3	$15.9M	Sell	380,534 -1,000,121	-72%	-$38.5M	0.02%	874
2018 Q2	$47.5M	Sell	1,380,655 -983,015	-42%	-$33.6M	0.06%	382
2018 Q1	$79.6M	Sell	2,363,670 -979,129	-29%	-$33.7M	0.11%	230
2017 Q4	$115M	Buy	3,342,799 +19,648	+0.6%	+$670K	0.16%	162
2017 Q3	$113M	Sell	3,323,151 -1,362,790	-29%	-$43.8M	0.17%	136
2017 Q2	$149M	Buy	4,685,941 +3,593,927	+329%	+$113M	0.25%	79
2017 Q1	$35.4M	Sell	1,092,014 -4,979,659	-82%	-$157M	0.06%	373
2016 Q4	$187M	Sell	6,071,673 -1,333,647	-18%	-$40.7M	0.32%	54
2016 Q3	$238M	Buy	7,405,320 +982,122	+15%	+$32.8M	0.42%	28
2016 Q2	$215M	Sell	6,423,198 -5,249,589	-45%	-$168M	0.4%	37
2016 Q1	$328M	Buy	11,672,787 +2,970,845	+34%	+$84.9M	0.59%	18
2015 Q4	$267M	Sell	8,701,942 -2,241,059	-20%	-$70.5M	0.4%	40
2015 Q3	$326M	Buy	10,943,001 +5,618,646	+106%	+$180M	0.48%	26
2015 Q2	$169M	Buy	5,324,355 +4,000,698	+302%	+$130M	0.25%	69
2015 Q1	$43.7M	Sell	1,323,657 -7,290,844	-85%	-$232M	0.07%	346
2014 Q4	$255M	Sell	8,614,501 -2,209,812	-20%	-$63.4M	0.33%	45
2014 Q3	$304M	Buy	10,824,313 +9,191,215	+563%	+$258M	0.39%	35
2014 Q2	$46M	Sell	1,633,098 -6,590,243	-80%	-$188M	0.06%	353
2014 Q1	$251M	Buy	8,223,341 +5,084,512	+162%	+$152M	0.36%	46
2013 Q4	$91.2M	Sell	3,138,829 -1,359,885	-30%	-$39.6M	0.12%	165
2013 Q3	$123M	Sell	4,498,714 -11,763,255	-72%	-$320M	0.2%	91
2013 Q2	$432M	Buy	+16,261,969	New	+$449M	0.81%	6

Other funds holding PFE

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

VPM

Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

Fisher Asset Management Camas, Washington $295B AUM 31.6% 1-Year Est. Return

Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return

Northern Trust Chicago, Illinois $757B AUM 28.64% 1-Year Est. Return

Massachusetts Financial Services Boston, Massachusetts $298B AUM 21.96% 1-Year Est. Return

State Farm Mutual Automobile Insurance Bloomington, Illinois $127B AUM 32.55% 1-Year Est. Return

D.E. Shaw & Co's PFE Position: Q1 2026 in Review

D.E. Shaw & Co increased its Pfizer (PFE) stake by 265% in Q1 2026, buying an estimated $241M and bringing the position to 12,467,262 shares worth $350M. The position accounts for 0.21% of the portfolio, ranked #89.

D.E. Shaw & Co first reported a position in PFE in Q2 2013 and has held it in 52 quarters since. The position peaked at $674M in Q1 2024. 2,937 funds tracked by Wall St. Rank hold PFE as of Q1 2026.

D.E. Shaw & Co held 12,467,262 shares of Pfizer worth $350M as of Q1 2026.
D.E. Shaw & Co bought 9,051,769 Pfizer shares in Q1 2026, an estimated $241M.
Pfizer made up 0.21% of D.E. Shaw & Co's portfolio in Q1 2026, its #89 holding.
D.E. Shaw & Co first reported a position in Pfizer in Q2 2013 and has held it in 52 quarters since.
D.E. Shaw & Co's Pfizer position peaked at $674M in Q1 2024.
2,937 funds tracked by Wall St. Rank held Pfizer as of Q1 2026.

Based on D.E. Shaw & Co's 13F filing for Q1 2026, filed 15 May 2026.