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2,952 hedge funds and large institutions have $106B invested in Pfizer in 2026 Q1 according to their latest regulatory filings, with 256 funds opening new positions, 1,303 increasing their positions, 1,088 reducing their positions, and 167 closing their positions.

New
Increased
Maintained
Reduced
Closed

53% more first-time investments, than exits

New positions opened: 256 | Existing positions closed: 167

52% more funds holding in top 10

Funds holding in top 10: 3147 (+16)

20% more repeat investments, than reductions

Existing positions increased: 1,303 | Existing positions reduced: 1,088

15% more call options, than puts

Call options by funds: $3.08B | Put options by funds: $2.68B

14% more capital invested

Capital invested by funds: $93B → $106B (+$12.6B)

1% more funds holding

Funds holding: 2,9132,952 (+39)

0.46% more ownership

Funds ownership: 65.68%66.15% (+0.46%)

Holders
2,952
Holders Change
+39
Holders Change %
+1.34%
% of All Funds
36.12%
Holding in Top 10
47
Holding in Top 10 Change
+16
Holding in Top 10 Change %
+51.61%
% of All Funds
0.58%
New
256
Increased
1,303
Reduced
1,088
Closed
167
Calls
$3.08B
Puts
$2.68B
Net Calls
+$400M
Net Calls Change
+$993M
Name Holding Trade Value Shares
Change
Change in
Stake
D.E. Shaw & Co
51
D.E. Shaw & Co
New York
$350M +$241M +9,051,769 +265%
AQR Capital Management
52
AQR Capital Management
Connecticut
$334M +$54.8M +2,059,402 +21%
Raymond James Financial
53
Raymond James Financial
Florida
$328M +$4.99M +187,503 +2%
Vanguard Asset Management
54
Vanguard Asset Management
$321M +$304M +11,424,753 New
Robeco Institutional Asset Management
55
Robeco Institutional Asset Management
Netherlands
$313M +$33.8M +1,267,791 +13%
California Public Employees Retirement System
56
California Public Employees Retirement System
California
$304M -$83.4M -3,133,806 -22%
Balyasny Asset Management
57
Balyasny Asset Management
Illinois
$294M +$51.3M +1,926,496 +23%
BNP Paribas Financial Markets
58
BNP Paribas Financial Markets
France
$278M -$176M -6,624,160 -40%
Stifel Financial
59
Stifel Financial
Missouri
$274M +$13.1M +491,819 +5%
Neuberger Berman Group
60
Neuberger Berman Group
New York
$272M +$62.1M +2,331,465 +32%
SG Americas Securities
61
SG Americas Securities
New York
$267M +$109M +4,100,329 +76%
Envestnet Asset Management
62
Envestnet Asset Management
Illinois
$262M +$18.6M +697,500 +8%
BIP
63
Brandes Investment Partners
California
$256M +$12.7M +478,043 +6%
California State Teachers Retirement System (CalSTRS)
64
California State Teachers Retirement System (CalSTRS)
California
$253M -$5.37M -201,827 -2%
RhumbLine Advisers
65
RhumbLine Advisers
Massachusetts
$249M +$1.75M +65,632 +0.7%
Fidelity International
66
Fidelity International
Bermuda
$246M -$13.3M -499,825 -5%
KBC Group
67
KBC Group
Belgium
$238M -$19.2M -721,799 -8%
Acadian Asset Management
68
Acadian Asset Management
Massachusetts
$236M +$176M +6,629,451 +374%
New York State Common Retirement Fund
69
New York State Common Retirement Fund
New York
$226M +$1.73M +65,000 +0.8%
Bank of Montreal
70
Bank of Montreal
Ontario, Canada
$215M -$52.6M -1,975,174 -20%
DekaBank Deutsche Girozentrale
71
DekaBank Deutsche Girozentrale
Germany
$211M
AIM
72
Artemis Investment Management
United Kingdom
$208M +$47.5M +1,782,628 +32%
Citadel Advisors
73
Citadel Advisors
Florida
$207M +$52M +1,952,489 +36%
SLAM
74
Swiss Life Asset Management
$206M +$13.1M +491,766 +7%
Voloridge Investment Management
75
Voloridge Investment Management
Florida
$196M +$73.1M +2,743,945 +65%

PFE Hedge Fund Activity: Q1 2026 in Review

2,952 of the 8,172 institutional investors tracked by Wall St. Rank reported a position in Pfizer (PFE) for Q1 2026, worth a combined $106B — up 14% from $93B a quarter earlier.

Buyers outnumbered sellers: 256 funds opened new PFE positions and 167 closed out — a net gain of 89 holders — while 1,303 added to existing stakes and 1,088 trimmed.

The largest buyer was Fisher Asset Management, adding an estimated $1.41B. The largest seller was BNP Paribas Financial Markets, cutting an estimated $176M.

  • 2,952 institutional investors held Pfizer (PFE) as of Q1 2026, up from 2,913 in Q4 2025.
  • Funds reported $106B of Pfizer stock for Q1 2026, up 14% quarter-over-quarter.
  • 256 funds opened new Pfizer positions in Q1 2026 and 167 closed out, a net change of +89 holders.
  • The largest Pfizer buyer in Q1 2026 was Fisher Asset Management, an estimated $1.41B added.
  • The largest Pfizer seller in Q1 2026 was BNP Paribas Financial Markets, an estimated $176M sold.

Based on aggregated 13F filings for Q1 2026.