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Penumbra
PEN

Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$148M +$149M +3,683,731 New
RG
2
Redmile Group
California
$51M +$63.2M +1,562,587 New
PHS
3
PFM Health Sciences
California
$15.3M +$15.4M +381,270 New
Capital World Investors
4
Capital World Investors
California
$14.5M +$14.6M +361,649 New
Morgan Stanley
5
Morgan Stanley
New York
$11.4M +$11.5M +284,900 New
Lord, Abbett & Co
6
Lord, Abbett & Co
New Jersey
$10.9M +$11M +271,303 New
RSCM
7
Rock Springs Capital Management
Maryland
$7.82M +$7.89M +195,000 New
AllianceBernstein
8
AllianceBernstein
Tennessee
$7.15M +$7.21M +178,215 New
Franklin Resources
9
Franklin Resources
California
$6.92M +$6.98M +172,564 New
ClearBridge Investments
10
ClearBridge Investments
New York
$4.81M +$4.85M +120,000 New
RIM
11
RS Investment Management
California
$4.64M +$4.68M +115,701 New
ACPU
12
Arrowgrass Capital Partners (US)
Delaware
$4.63M +$4.68M +115,588 New
Federated Hermes
13
Federated Hermes
Pennsylvania
$4.41M +$4.45M +110,000 New
O
14
OppenheimerFunds
New York
$4.26M +$4.3M +106,300 New
NHAS
15
Novo Holdings A/S
Denmark
$4.21M +$4.24M +104,944 New
Capital Research Global Investors
16
Capital Research Global Investors
California
$4.15M +$4.19M +103,589 New
Adage Capital Partners
17
Adage Capital Partners
Massachusetts
$4.01M +$4.04M +100,000 New
DM
18
Deerfield Management
New York
$4.01M +$4.04M +100,000 New
Invesco
19
Invesco
Georgia
$4.01M +$4.04M +100,000 New
Primecap Management
20
Primecap Management
California
$4.01M +$4.04M +100,000 New
Jennison Associates
21
Jennison Associates
New York
$2.61M +$2.63M +65,000 New
WRF
22
Waddell & Reed Financial
Kansas
$2M +$2.02M +50,000 New
Millennium Management
23
Millennium Management
New York
$1.14M +$1.15M +28,425 New
UBS AM
24
UBS AM
Illinois
$1.05M +$1.06M +26,171 New
PVI
25
Pura Vida Investments
New York
$1.03M +$1.04M +25,800 New
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