|
1
|
RA Capital Management
Boston,
Massachusetts
|
$792M
|
+$799M
|
+28,933,371
|
New
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$282M
|
+$284M
|
+10,292,735
|
New
|
|
|
3
|
Arch Venture Management
Chicago,
Illinois
|
$176M
|
+$177M
|
+6,412,780
|
New
|
|
|
4
|
venBio Partners
San Francisco,
California
|
$144M
|
+$145M
|
+5,266,697
|
New
|
|
|
5
|
Alphabet Inc
Mountain View,
California
|
$135M
|
+$136M
|
+4,919,498
|
New
|
|
|
6
|
Nextech Invest
Zurich,
Switzerland
|
$128M
|
+$129M
|
+4,663,176
|
New
|
|
|
7
|
Cormorant Asset Management
Boston,
Massachusetts
|
$126M
|
+$128M
|
+4,615,612
|
New
|
|
|
8
|
Regeneron Pharmaceuticals
Tarrytown,
New York
|
$114M
|
+$115M
|
+4,166,666
|
New
|
|
|
9
|
Siren LLC
Greenwich,
Connecticut
|
$81.9M
|
+$82.7M
|
+2,992,259
|
New
|
|
|
10
|
Farallon Capital Management
San Francisco,
California
|
$64.8M
|
+$65.4M
|
+2,368,200
|
New
|
|
|
11
|
|
$62.7M
|
+$63.4M
|
+2,296,547
|
New
|
|
|
12
|
Frazier Life Sciences Management
Palo Alto,
California
|
$52.6M
|
+$53.1M
|
+1,920,805
|
New
|
|
|
13
|
Deerfield Management
New York
|
$51.5M
|
+$52M
|
+1,880,704
|
New
|
|
|
14
|
General Catalyst Group Management
Cambridge,
Massachusetts
|
$43.8M
|
+$44.2M
|
+1,600,937
|
New
|
|
|
15
|
General Atlantic
New York
|
$42.1M
|
+$42.5M
|
+1,538,461
|
New
|
|
|
16
|
Soleus Capital Management
Greenwich,
Connecticut
|
$40.1M
|
+$40.5M
|
+1,465,070
|
New
|
|
|
17
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$35.6M
|
+$36M
|
+1,302,479
|
New
|
|
|
18
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$31.7M
|
+$32M
|
+1,156,962
|
New
|
|
|
19
|
|
$30.4M
|
+$28.8M
|
+1,042,772
|
New
|
|
|
20
|
Foresite Capital Management VI
Larkspur,
California
|
$27.3M
|
+$27.6M
|
+999,044
|
New
|
|
|
21
|
Catalio Capital Management
New York
|
$22.6M
|
+$22.8M
|
+824,043
|
New
|
|
|
22
|
AllianceBernstein
Nashville,
Tennessee
|
$22.2M
|
+$22.4M
|
+810,279
|
New
|
|
|
23
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$20.6M
|
+$20.8M
|
+751,947
|
New
|
|
|
24
|
|
$17.7M
|
+$17.8M
|
+645,690
|
New
|
|
|
25
|
|
$17.1M
|
+$17.3M
|
+625,000
|
New
|
|
