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Pacific Biosciences

215 hedge funds and large institutions have $374M invested in Pacific Biosciences in 2025 Q4 according to their latest regulatory filings, with 43 funds opening new positions, 69 increasing their positions, 49 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

303% more call options, than puts

Call options by funds: $7.02M | Put options by funds: $1.74M

57% more capital invested

Capital invested by funds: $238M → $374M (+$136M)

41% more repeat investments, than reductions

Existing positions increased: 69 | Existing positions reduced: 49

34% more first-time investments, than exits

New positions opened: 43 | Existing positions closed: 32

4.49% more ownership

Funds ownership: 62%66.49% (+4.5%)

3% more funds holding

Funds holding: 208215 (+7)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
215
Holders Change
+7
Holders Change %
+3.37%
% of All Funds
2.62%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
43
Increased
69
Reduced
49
Closed
32
Calls
$7.02M
Puts
$1.74M
Net Calls
+$5.28M
Net Calls Change
+$3.44M
Name Holding Trade Value Shares
Change
Change in
Stake
AIM
1
ARK Investment Management
Florida
$69.7M +$12.2M +6,340,125 +21%
BlackRock
2
BlackRock
New York
$43.7M +$1.25M +649,218 +3%
SoftBank Group
3
SoftBank Group
Japan
$38.2M
Vanguard Group
4
Vanguard Group
Pennsylvania
$31.9M +$1.26M +657,342 +4%
NAMA
5
Nikko Asset Management Americas
New York
$14.6M -$1.67M -868,978 -10%
Sumitomo Mitsui Trust Group
6
Sumitomo Mitsui Trust Group
Japan
$14.6M -$1.67M -868,978 -10%
Geode Capital Management
7
Geode Capital Management
Massachusetts
$13.2M +$331K +172,089 +2%
State Street
8
State Street
Massachusetts
$11.1M +$4.96K +2,579 +0%
D.E. Shaw & Co
9
D.E. Shaw & Co
New York
$8.3M +$8.53M +4,438,273 New
Millennium Management
10
Millennium Management
New York
$8.12M -$1.1M -572,226 -12%
CC
11
Casdin Capital
New York
$7.9M +$6.73M +3,500,000 +484%
Renaissance Technologies
12
Renaissance Technologies
New York
$7.2M +$7.4M +3,850,600 New
UBS Group
13
UBS Group
Switzerland
$5.93M +$3.22M +1,674,320 +112%
Citadel Advisors
14
Citadel Advisors
Florida
$5.92M +$1.28M +667,887 +27%
Point72 Asset Management
15
Point72 Asset Management
Connecticut
$5.53M +$5.68M +2,957,400 New
Two Sigma Investments
16
Two Sigma Investments
New York
$5.38M +$4.76M +2,475,418 +616%
Susquehanna International Group
17
Susquehanna International Group
Pennsylvania
$4.88M +$2.38M +1,236,284 +90%
KOC
18
Koss-Olinger Consulting
Florida
$4.86M -$1.35M -700,000 -21%
Charles Schwab
19
Charles Schwab
California
$4.61M +$74K +38,499 +2%
Morgan Stanley
20
Morgan Stanley
New York
$4.51M +$3.77M +1,959,325 +434%
Northern Trust
21
Northern Trust
Illinois
$3.83M -$465K -242,057 -11%
IEFM
22
IQ EQ Fund Management
Ireland
$3.54M +$1.16M +606,239 +47%
Bank of America
23
Bank of America
North Carolina
$3.47M +$734K +382,124 +26%
AG
24
Amiral Gestion
France
$3.21M
Jane Street
25
Jane Street
New York
$2.81M +$2.43M +1,263,495 +533%