OSI Systems
OSIS
358 hedge funds and large institutions have $4.8B invested in OSI Systems in 2025 Q4 according to their latest regulatory filings, with 63 funds opening new positions, 132 increasing their positions, 108 reducing their positions, and 45 closing their positions.
40% more first-time investments, than exits
New positions opened: 63 | Existing positions closed: 45
22% more repeat investments, than reductions
Existing positions increased: 132 | Existing positions reduced: 108
21% more call options, than puts
Call options by funds: $10.5M | Put options by funds: $8.65M
3% more funds holding
Funds holding: 349 → 358 (+9)
3% more capital invested
Capital invested by funds: $4.66B → $4.8B (+$141M)
0.32% less ownership
Funds ownership: 111.11% → 110.79% (-0.32%)
40% less funds holding in top 10
Funds holding in top 10: 5 → 3 (-2)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Fidelity Investments
Boston,
Massachusetts
|
+$148M |
| 2 |
William Blair Investment Management
Chicago,
Illinois
|
+$50M |
| 3 |
DCM
Driehaus Capital Management
Chicago,
Illinois
|
+$23.2M |
| 4 |
Invesco
Atlanta,
Georgia
|
+$19.3M |
| 5 |
BlackRock
New York
|
+$15.1M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Janus Henderson Group
London,
|
-$64.7M |
| 2 |
Macquarie Group
Sydney, NSW 2000,
Australia
|
-$52.1M |
| 3 |
ClearBridge Investments
New York
|
-$15.5M |
| 4 |
Brown Advisory
Baltimore,
Maryland
|
-$15.3M |
| 5 |
Two Sigma Investments
New York
|
-$14.7M |
OSIS Hedge Fund Activity: Q4 2025 in Review
358 of the 8,266 institutional investors tracked by Wall St. Rank reported a position in OSI Systems (OSIS) for Q4 2025, worth a combined $4.8B — up 3% from $4.66B a quarter earlier.
Buyers outnumbered sellers: 63 funds opened new OSIS positions and 45 closed out — a net gain of 18 holders — while 132 added to existing stakes and 108 trimmed.
The largest buyer was Fidelity Investments, adding an estimated $148M. The largest seller was Janus Henderson Group, cutting an estimated $64.7M.
- 358 institutional investors held OSI Systems (OSIS) as of Q4 2025, up from 349 in Q3 2025.
- Funds reported $4.8B of OSI Systems stock for Q4 2025, up 3% quarter-over-quarter.
- 63 funds opened new OSI Systems positions in Q4 2025 and 45 closed out, a net change of +18 holders.
- The largest OSI Systems buyer in Q4 2025 was Fidelity Investments, an estimated $148M added.
- The largest OSI Systems seller in Q4 2025 was Janus Henderson Group, an estimated $64.7M sold.
Based on aggregated 13F filings for Q4 2025.