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ORKA

Oruka Therapeutics

143 hedge funds and large institutions have $1.6B invested in Oruka Therapeutics in 2025 Q4 according to their latest regulatory filings, with 46 funds opening new positions, 54 increasing their positions, 16 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

475% more first-time investments, than exits

New positions opened: 46 | Existing positions closed: 8

238% more repeat investments, than reductions

Existing positions increased: 54 | Existing positions reduced: 16

83% more capital invested

Capital invested by funds: $876M → $1.6B (+$726M)

40% more funds holding in top 10

Funds holding in top 10: 57 (+2)

36% more funds holding

Funds holding: 105143 (+38)

13% more call options, than puts

Call options by funds: $527K | Put options by funds: $467K

12.47% less ownership

Funds ownership: 121.65%109.18% (-12%)

Holders
143
Holders Change
+38
Holders Change %
+36.19%
% of All Funds
1.74%
Holding in Top 10
7
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+40%
% of All Funds
0.09%
New
46
Increased
54
Reduced
16
Closed
8
Calls
$527K
Puts
$467K
Net Calls
+$60K
Net Calls Change
+$2.59M
Name Holding Trade Value Shares
Change
Change in
Stake
CAM
26
Cormorant Asset Management
Massachusetts
$16.2M
SAM
27
Synergy Asset Management
Washington
$13.9M +$12.8M +458,946 New
SOCM
28
SR One Capital Management
Pennsylvania
$13M
CS
29
Candriam SCA
Luxembourg
$12.1M +$934K +33,515 +9%
CCC
30
Cable Car Capital
California
$12.1M -$2.79M -100,000 -20%
Charles Schwab
31
Charles Schwab
California
$9.99M +$2.3M +82,570 +33%
Northern Trust
32
Northern Trust
Illinois
$8.51M +$1.71M +61,195 +28%
UBS Group
33
UBS Group
Switzerland
$8.21M +$5.14M +184,453 +213%
SCM
34
Soleus Capital Management
Connecticut
$5.76M +$5.29M +190,000 New
GPP
35
Great Point Partners
Connecticut
$5.56M
Barclays
36
Barclays
United Kingdom
$5.25M +$2.17M +77,999 +82%
Invesco
37
Invesco
Georgia
$4.34M +$3.53M +126,803 +777%
Bank of America
38
Bank of America
North Carolina
$4.22M +$1.68M +60,277 +76%
LP
39
Longaeva Partners
Illinois
$3.88M +$3.57M +128,110 New
MAP
40
Moody Aldrich Partners
Massachusetts
$3.84M +$3.53M +126,812 New
Morgan Stanley
41
Morgan Stanley
New York
$3.7M -$352K -12,635 -9%
Deutsche Bank
42
Deutsche Bank
Germany
$3.62M +$2.71M +97,210 +439%
KCM
43
Kalehua Capital Management
Texas
$3.59M +$3.3M +118,524 New
SCM
44
Sio Capital Management
New York
$3.58M +$3.29M +118,126 New
Bank of New York Mellon
45
Bank of New York Mellon
New York
$3.46M +$1.21M +43,541 +62%
Alyeska Investment Group
46
Alyeska Investment Group
Illinois
$3.03M +$2.79M +100,000 New
Goldman Sachs
47
Goldman Sachs
New York
$2.82M +$2.04M +73,220 +370%
N
48
Nuveen
North Carolina
$2.62M +$1.42M +51,034 +145%
B
49
Braidwell
Connecticut
$2.57M -$36.2M -1,297,555 -94%
Wellington Management Group
50
Wellington Management Group
Massachusetts
$2.57M -$178K -6,378 -7%