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OptimizeRx

125 hedge funds and large institutions have $274M invested in OptimizeRx in 2025 Q3 according to their latest regulatory filings, with 37 funds opening new positions, 29 increasing their positions, 37 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

165% more call options, than puts

Call options by funds: $3.27M | Put options by funds: $1.23M

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

68% more first-time investments, than exits

New positions opened: 37 | Existing positions closed: 22

63% more capital invested

Capital invested by funds: $168M → $274M (+$106M)

14% more funds holding

Funds holding: 110125 (+15)

4.56% more ownership

Funds ownership: 67.35%71.91% (+4.6%)

22% less repeat investments, than reductions

Existing positions increased: 29 | Existing positions reduced: 37

Holders
125
Holders Change
+15
Holders Change %
+13.64%
% of All Funds
1.64%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
37
Increased
29
Reduced
37
Closed
22
Calls
$3.27M
Puts
$1.23M
Net Calls
+$2.03M
Net Calls Change
+$193K
Name Holding Trade Value Shares
Change
Change in
Stake
Balyasny Asset Management
126
Balyasny Asset Management
Illinois
-$2.11M -156,338 Closed
CCIA
127
Campbell & Co Investment Adviser
Maryland
-$653K -48,397 Closed
Connor, Clark & Lunn Investment Management (CC&L)
128
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
-$418K -30,944 Closed
Susquehanna International Group
129
Susquehanna International Group
Pennsylvania
-$455K -28,662 Closed
XT
130
XTX Topco
Cayman Islands
-$344K -25,493 Closed
Walleye Capital
131
Walleye Capital
New York
-$339K -25,108 Closed
Two Sigma Advisers
132
Two Sigma Advisers
New York
-$311K -23,023 Closed
MCM
133
Massar Capital Management
Connecticut
-$297K -22,000 Closed
Verition Fund Management
134
Verition Fund Management
Connecticut
-$294K -21,792 Closed
WG
135
Winton Group
United Kingdom
-$286K -21,208 Closed
Millennium Management
136
Millennium Management
New York
-$238K -17,593 Closed
CC
137
Centiva Capital
New York
-$166K -12,274 Closed
HF
138
HRT Financial
New York
-$164K -12,201 Closed
TI
139
Trexquant Investment
Connecticut
-$152K -11,257 Closed
CC
140
Corton Capital
Ontario, Canada
-$138K -10,194 Closed
Walleye Trading
141
Walleye Trading
New York
-$133K -9,887 Closed
QT
142
Quantbot Technologies
New York
-$44.4K -3,292 Closed
National Bank of Canada
143
National Bank of Canada
Quebec, Canada
-$35.3K -2,619 Closed
QL
144
Quarry LP
New York
-$17.8K -1,316 Closed
CCMI
145
Creative Capital Management Investments
California
-$2.69K -199 Closed
BIG
146
Brooklyn Investment Group
New York
-$959 -71 Closed
TPWA
147
Twin Peaks Wealth Advisors
California
-$49 -3 Closed

OPRX Hedge Fund Activity: Q3 2025 in Review

125 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in OptimizeRx (OPRX) for Q3 2025, worth a combined $274M — up 63% from $168M a quarter earlier.

Buyers outnumbered sellers: 37 funds opened new OPRX positions and 22 closed out — a net gain of 15 holders — while 29 added to existing stakes and 37 trimmed.

The largest buyer was CenterBook Partners, opening a new position worth an estimated $4.9M. The largest seller was Schonfeld Strategic Advisors, cutting an estimated $2.89M.

  • 125 institutional investors held OptimizeRx (OPRX) as of Q3 2025, up from 110 in Q2 2025.
  • Funds reported $274M of OptimizeRx stock for Q3 2025, up 63% quarter-over-quarter.
  • 37 funds opened new OptimizeRx positions in Q3 2025 and 22 closed out, a net change of +15 holders.
  • The largest OptimizeRx buyer in Q3 2025 was CenterBook Partners, an estimated $4.9M added.
  • The largest OptimizeRx seller in Q3 2025 was Schonfeld Strategic Advisors, an estimated $2.89M sold.

Based on aggregated 13F filings for Q3 2025.