Two Sigma Advisers
OPRX icon

Two Sigma Advisers’s OptimizeRx OPRX Stock Holding History

Two Sigma Advisers’s Portfolio OPRX Stock Details OPRX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		– Sell
-23,023
Closed -$311K – 2548
2025
Q2 		$311K Buy
+23,023
New +$252K ﹤0.01% 1945
2024
Q2 		– Sell
-12,900
Closed -$157K – 2618
2024
Q1 		$157K Sell
12,900
-22,100
-63% -$321K ﹤0.01% 2250
2023
Q4 		$501K Sell
35,000
-37,000
-51% -$355K ﹤0.01% 1923
2023
Q3 		$560K Sell
72,000
-74,600
-51% -$812K ﹤0.01% 1755
2023
Q2 		$2.09M Sell
146,600
-44,900
-23% -$639K 0.01% 1178
2023
Q1 		$2.8M Sell
191,500
-5,500
-3% -$92K 0.01% 1084
2022
Q4 		$3.31M Sell
197,000
-120,700
-38% -$2.09M 0.01% 961
2022
Q3 		$4.71M Buy
317,700
+237,100
+294% +$4.69M 0.01% 765
2022
Q2 		$2.21M Buy
80,600
+16,200
+25% +$480K 0.01% 1161
2022
Q1 		$2.43M Buy
64,400
+38,200
+146% +$1.69M 0.01% 1145
2021
Q4 		$1.63M Sell
26,200
-82,500
-76% -$6.25M ﹤0.01% 1298
2021
Q3 		$9.3M Sell
108,700
-53,800
-33% -$3.38M 0.02% 539
2021
Q2 		$10.1M Sell
162,500
-9,200
-5% -$468K 0.03% 562
2021
Q1 		$8.37M Buy
171,700
+151,810
+763% +$7.32M 0.02% 642
2020
Q4 		$620K Buy
+19,890
New +$487K ﹤0.01% 1788

Other funds holding OPRX

WCA
Whetstone Capital Advisors Shawnee Mission, Kansas $266M AUM 44.06% 1-Year Est. Return
BlackRock
BlackRock New York $5.7T AUM 30.48% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
RA
Royce & Associates New York $10.1B AUM 42.88% 1-Year Est. Return
KCM
Kennedy Capital Management St Louis, Missouri $4.72B AUM 36.69% 1-Year Est. Return
William Blair & Company
William Blair & Company Chicago, Illinois $34.9B AUM 18.88% 1-Year Est. Return
RHJA
Rice Hall James & Associates San Diego, California $1.8B AUM 36.16% 1-Year Est. Return
PHP
Parkman Healthcare Partners Stamford, Connecticut $965M AUM 79.46% 1-Year Est. Return
MHP
Manatuck Hill Partners Westport, Connecticut $305M AUM 95.53% 1-Year Est. Return
Dimensional Fund Advisors
Dimensional Fund Advisors Austin, Texas $481B AUM 30.42% 1-Year Est. Return