|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$101M
|
+$28.6M
|
+986,192
|
+43%
|
|
|
2
|
Baker Bros. Advisors
New York
|
$58.9M
|
–
|
–
|
–
|
|
|
3
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$34M
|
+$18.8M
|
+648,370
|
+143%
|
|
|
4
|
Hillhouse Investment Management
Grand Cayman,
Cayman Islands
|
$21.6M
|
–
|
–
|
–
|
|
|
5
|
Boxer Capital
San Diego,
California
|
$15.2M
|
–
|
–
|
–
|
|
|
6
|
Temasek Holdings
Singapore
|
$11.7M
|
–
|
–
|
–
|
|
|
7
|
Brown Advisory
Baltimore,
Maryland
|
$10.8M
|
+$6.93M
|
+238,604
|
+212%
|
|
|
8
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$6.93M
|
–
|
–
|
–
|
|
|
9
|
|
$5.24M
|
–
|
–
|
–
|
|
|
10
|
RA Capital Management
Boston,
Massachusetts
|
$5.24M
|
–
|
–
|
–
|
|
|
11
|
EcoR1 Capital
San Francisco,
California
|
$5.04M
|
-$346K
|
-11,910
|
-7%
|
|
|
12
|
Prince Street Capital Management
New York
|
$4.17M
|
–
|
–
|
–
|
|
|
13
|
Perceptive Advisors
New York
|
$4.07M
|
+$3.83M
|
+132,057
|
New
|
|
|
14
|
VHCP Management II
New York
|
$3.67M
|
–
|
–
|
–
|
|
|
15
|
Tekla Capital Management
Boston,
Massachusetts
|
$3.6M
|
–
|
–
|
–
|
|
|
16
|
DAFNA Capital Management
Los Angeles,
California
|
$2.78M
|
+$2.04M
|
+70,142
|
+351%
|
|
|
17
|
CQS Cayman
Camana Bay, Grand Cayman,
Cayman Islands
|
$2.26M
|
-$29K
|
-1,000
|
-1%
|
|
|
18
|
Baillie Gifford & Co
Edinburgh,
United Kingdom
|
$2.12M
|
+$18.4K
|
+635
|
+0.9%
|
|
|
19
|
Pine River Capital Management
Minnetonka,
Minnesota
|
$1.9M
|
-$92.9K
|
-3,200
|
-5%
|
|
|
20
|
|
$1.57M
|
–
|
–
|
–
|
|
|
21
|
Board of Trustees of The Leland Stanford Junior University
Redwood City,
California
|
$1.54M
|
–
|
–
|
–
|
|
|
22
|
Manulife (Manufacturers Life Insurance)
Canada,
Ontario, Canada
|
$1.46M
|
–
|
–
|
–
|
|
|
23
|
Ariose Capital Management
Central, Hong Kong,
Hong Kong
|
$1.26M
|
+$1.12M
|
+38,599
|
New
|
|
|
24
|
State Street
Boston,
Massachusetts
|
$981K
|
+$925K
|
+31,852
|
New
|
|
|
25
|
Renaissance Technologies
New York
|
$952K
|
+$897K
|
+30,900
|
New
|
|
